Evidence map›Paper›PMID 32794047›Full record

ArticleSurgical endoscopy2021

Ineffective esophageal motility is not a contraindication to total fundoplication.

Anne-Sophie Laliberte, Brian E Louie, Candice L Wilshire, Alexander S Farivar, Adam J Bograd, Ralph W Aye

Abstract read
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A practical approach to ineffective esophageal motility.Neurogastroenterology and motility · 2024
    Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Anne-Sophie LaliberteDivision of Thoracic Surgery, Swedish Cancer Institute and Medical Center, 1101 Madison Street, Suite 900, Seattle, WA, 98104, USA.
Brian E LouieDivision of Thoracic Surgery, Swedish Cancer Institute and Medical Center, 1101 Madison Street, Suite 900, Seattle, WA, 98104, USA.
Candice L WilshireDivision of Thoracic Surgery, Swedish Cancer Institute and Medical Center, 1101 Madison Street, Suite 900, Seattle, WA, 98104, USA.
Alexander S FarivarDivision of Thoracic Surgery, Swedish Cancer Institute and Medical Center, 1101 Madison Street, Suite 900, Seattle, WA, 98104, USA.
Adam J BogradDivision of Thoracic Surgery, Swedish Cancer Institute and Medical Center, 1101 Madison Street, Suite 900, Seattle, WA, 98104, USA.
Ralph W AyeDivision of Thoracic Surgery, Swedish Cancer Institute and Medical Center, 1101 Madison Street, Suite 900, Seattle, WA, 98104, USA. Ralph.Aye@swedish.org.ORCID http://orcid.org/0000-0003-3726-6673
Swedish Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIneffective esophageal motility (IEM) is a physiologic diagnosis and is a component of the Chicago Classification. It has a strong association with gastroesophageal reflux and may be found during work-up for anti-reflux surgery. IEM implies a higher risk of post-op dysphagia if a total fundoplication is done. We hypothesized that IEM is not predictive of dysphagia following fundoplication and that it is safe to perform total fundoplication in appropriately selected patients.

methodsRetrospective chart review of patients who underwent total fundoplication between September 2012 and December 2018 in a single foregut surgery center and who had IEM on preoperative manometry. We excluded patients who had partial fundoplication, previous foregut surgery, other causes of dysphagia or an esophageal lengthening procedure. Dysphagia was assessed using standardized Dakkak score ≤ 40 and GERD-HRQL question 7 ≥ 3.

resultsTwo hundred patients were diagnosed with IEM and 31 met the inclusion criteria. Median follow-up: 706 days (IQR 278-1348 days). No preoperative factors, including subjective dysphagia, transit on barium swallow, or individual components of manometry showed statistical correlation with postoperative dysphagia. Of 9 patients with preoperative dysphagia, 2 (22%) had persistent postoperative dysphagia and 7 had resolution. Of 22 patients without preoperative dysphagia, 3 (14%) developed postoperative dysphagia; for a combined rate of 16%. No patient needed re-intervention beyond early recovery or required reoperation for dysphagia during the follow-up period.

conclusionIn appropriately selected patients, when total fundoplication is performed in the presence of preoperative IEM, the rate of long-term postoperative dysphagia is similar to the reported rate of dysphagia without IEM. With appropriate patient selection, total fundoplication may be performed in patients with IEM without a disproportionate increase in postoperative dysphagia. The presence of preoperative IEM should not be rigidly applied as a contraindication to a total fundoplication.

Indexed as

Deglutition DisordersEsophageal Motility DisordersGastroesophageal RefluxContraindicationsFundoplicationHumansManometryRetrospective StudiesIEMIneffective esophageal motilityTotal fundoplication

Identifiers

PMID32794047
OpenAlexW3048785652

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.