Evidence map›Paper›PMID 32794002›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2021

Symptomatology of COVID-19 from the otorhinolaryngology perspective: a survey of 223 SARS-CoV-2 RNA-positive patients.

Egehan Salepci, Bilge Turk, Safiye Nur Ozcan, Merve Ekici Bektas, Alperen Aybal, Ilyas Dokmetas, Suat Turgut

Abstract read
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Symptoms and Otorhinolaryngological Sequalae in Long Covid.International archives of otorhinolaryngology · 2025
    Article
  7. Post -acute sequalae of COVID-19 and cardiac outcomes in U. S. military members.International journal of cardiology. Cardiovascular risk and prevention · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Prevalence of General and Otorhinolaryngological Symptoms Post-COVID-19 Regarding the Time of Presentation.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  12. Changing Trends in COVID-19 Symptomatology: A Survey-Based Analysis.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  13. Incidence of Sino-Nasal Symptoms in COVID-19 Patients.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  14. Prevalence of Otorhinolaryngological Symptoms in Covid 19 Patients.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  15. Article
  16. Article
  17. Observational
  18. Observational
  19. Otologic and vestibular symptoms in COVID-19: A scoping review.World journal of otorhinolaryngology - head and neck surgery · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Egehan SalepciDepartment of Otorhinolaryngology, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Etfal Sk. No: 1, 34371, Sisli, Istanbul, Turkey. egehansalepci@yahoo.com.ORCID http://orcid.org/0000-0003-1923-0263
Bilge TurkDepartment of Otorhinolaryngology, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Etfal Sk. No: 1, 34371, Sisli, Istanbul, Turkey.
Safiye Nur OzcanDepartment of Clinical Microbiology and Infectious Diseases, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, 34371, Sisli, Istanbul, Turkey.
Merve Ekici BektasDepartment of Otorhinolaryngology, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Etfal Sk. No: 1, 34371, Sisli, Istanbul, Turkey.
Alperen AybalDepartment of Otorhinolaryngology, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Etfal Sk. No: 1, 34371, Sisli, Istanbul, Turkey.
Ilyas DokmetasDepartment of Clinical Microbiology and Infectious Diseases, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, 34371, Sisli, Istanbul, Turkey.
Suat TurgutDepartment of Otorhinolaryngology, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Etfal Sk. No: 1, 34371, Sisli, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine prevalence, severity, duration, and time from onset to diagnosis of general and Otorhinolaryngologic symptoms related to COVID-19 in whole disease spectrum: from mild to critical patients.

methodsAll adult patients with positive SARS-CoV-2 RNA found in nasopharyngeal and oropharyngeal swabs between March 10 and April 21, 2020 were surveyed by the authors for new onset symptoms during disease course. Demographic features, general symptoms, and Otorhinolaryngological symptoms were evaluated and compared by disease severity.

resultsOf 223 included patients, 18.4% had mild, 61.4%; moderate, 14.3%; severe, and 5.8%; critical disease. Median age was 51 (range 20-93), 113 (50.7%) were male and 110 (49.3%) were female. The most common general symptoms were fatigue, cough, and fever with respective frequencies of 71.3%, 54.3%, and 50.7%. The most common Otorhinolaryngologic symptoms were taste loss, smell loss, and sore throat with respective frequencies of 34.5%, 31.8%, and 26%. Fatigue, fever, and dyspnea were more common in severe-critical patients compared to mild-moderate patients (p = 0.029, p = 0.016, and p < 0.001, respectively). Only smell loss was more common in mild-moderate group (p = 0.003). Prevalence of other symptoms did not differ between groups. Symptom durations and onset time to diagnosis varied.

conclusionWhen compared to the previous studies, while general symptoms were less common, Otorhinolaryngologic symptoms were more common in our study population. Considering high infection risks, Otorhinolaryngologists should be aware of COVID-19 patients presenting with Otorhinolaryngologic complaints.

Indexed as

COVID-19OtolaryngologyAdultAgedAged, 80 and overCoughFemaleHumansMaleMiddle AgedOlfaction DisordersRNA, ViralSARS-CoV-2Young AdultRNA, ViralCOVID-19ENT symptomsRespiratory symptomsSmell lossTaste loss

Identifiers

PMID32794002
PMCPMC7426010

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.