Evidence map›Paper›PMID 32793971›Full record

ArticleRheumatology (Oxford, England)2021

Which factors predict discordance between a patient and physician on a gout flare?

Aprajita Jagpal, Elizabeth J Rahn, Amy S Mudano, Nicola Dalbeth, William Taylor, Kenneth G Saag, Jasvinder A Singh, Lorenzo Cavagna, Till Uhlig, Fernando Perez-Ruiz and 11 more

Open access · greenAbstract read
In one paragraph

Article in Rheumatology (Oxford, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 13 institutions in 11 countries.

Aprajita JagpalDivision of Rheumatology, University of Alabama, Birmingham, Birmingham, AL, USA.
Elizabeth J RahnDivision of Rheumatology, University of Alabama, Birmingham, Birmingham, AL, USA.
Amy S MudanoDivision of Rheumatology, University of Alabama, Birmingham, Birmingham, AL, USA.
Nicola DalbethDepartment of Rheumatology, University of Auckland, Auckland, New Zealand.
William TaylorDepartment of Rheumatology, University of Otago, Wellington, New Zealand.
Kenneth G SaagDivision of Rheumatology, University of Alabama, Birmingham, Birmingham, AL, USA.
Jasvinder A SinghDivision of Rheumatology, University of Alabama, Birmingham, Birmingham, AL, USA.
Lorenzo CavagnaDepartment of Rheumatology, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy.
Till UhligDepartment of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway.
Fernando Perez-RuizDivision of Rheumatology, Osakidetza, OSI-EEC, Cruces University Hospital, Rheumatology Division, Biskay, Spain.
Geraldine McCarthyDepartment of Medicine, University College Dublin and Consultant Rheumatologist, Mater Misericordiae University Hospital Dublin, Ireland.
Martijn GerritsenDepartment of Rheumatology, Reade, Amsterdam, The Netherlands.
Lisa StampDepartment of Medicine, University of Otago, Christchurch, New Zealand.
Janitzia Vazquez MelladoServicio de Reumatología, Hospital General de Mexico, Mexico City, Mexico.
Chingtsai LinDivision of Allergy, Immunology and Rheumatology, Taichung Veterans General Hospital, Taichung, Taiwan.
Ana Beatriz Vargas-SantosRheumatology, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.
Worawit LouthrenooFaculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Tuhina NeogiDivision of Rheumatology, Boston University School of Medicine, Boston, MA, USA.
Yi-Hsing ChenDivision of Allergy, Immunology and Rheumatology, Taichung Veterans General Hospital, Taichung, Taiwan.
Geraldo da Rocha Castelar-PinheiroDepartment of Medicine, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.
Angelo GaffoDivision of Rheumatology, University of Alabama, Birmingham, Birmingham, AL, USA.
University of Alabama at Birmingham · USTaichung Veterans General Hospital · TWUniversidade do Estado do Rio de Janeiro · BRUniversity of Otago · NZBoston University · USChiang Mai University · THDiakonhjemmet Hospital · NOHospital General de México · MXOsakidetza · ESPoliclinico San Matteo Fondazione · ITReade · NLUniversity College Dublin · IEUniversity of Auckland · NZ

Funding

Research and Evaluation Support Core Unit (RESCU Core)P30AR072571 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Michael Paul Lavalley · 2019 to 2026
$6.9M
NIAMS NIH HHS P30 AR072571
6 · The paper itself

Abstract

objectiveTo investigate the factors associated with discordance between patient and physician on the presence of a gout flare.

methodsPatients' self-reports of current gout flares were assessed with the question, 'Are you having a gout flare today?' which was then compared with a concurrent, blinded, physician's assessment. Based on agreement or disagreement with physicians on the presence of a gout flare, flares were divided into concordant and discordant groups, respectively. Within the discordant group, two subgroups-patient-reported flare but the physician disagreed and physician-reported flare but the patient disagreed-were identified. The factors associated with discordance were analysed with multivariable logistic regression analysis.

resultsOf 268 gout flares, 81 (30.2%) flares were discordant, with either patient or physician disagreeing on the presence of a flare. Of the discordant flares, in 57 (70.4%) the patient reported a flare but the physician disagreed. In multivariable logistic regression analysis adjusted for demographics, disagreement among patients and physicians on the presence of a gout flare was associated with lower pain scores at rest [odds ratio (OR) for each point increase on 0-10 point pain scale 0.81 (95% Wald CI 0.73, 0.90), P < 0.0001] and less presence of joint swelling [OR 0.24 (95% CI 0.10, 0.61), P = 0.003] or joint warmth [OR 0.39 (95% CI 0.20, 0.75), P = 0.005].

conclusionAlthough patients and physicians generally agree about the presence of gout flare, discordance may occur in the setting of low pain scores and in the absence of swollen or warm joints.

Indexed as

Self ReportFemaleGoutHumansMaleMiddle AgedPain MeasurementPhysiciansSymptom Flare Upacute gout flareGoutpatient perspective

Identifiers

PMID32793971
PMCPMC10687509
OpenAlexW3049063172

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.