ArticleAnnals of translational medicine2020
Hidradenitis suppurativa and psychiatric comorbidities, suicides and substance abuse: systematic review and meta-analysis.
Article in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Completed suicide in patients with skin disease: A systematic review and meta-analysis.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026Pooled it
- A state-of-the-art systematic review of cancer in hidradenitis suppurativa.Annals of medicine · 2024Pooled it
- Individual-level risk factors for suicide mortality in the general population: an umbrella review.The Lancet. Public health · 2023Pooled it
- Psychiatric Comorbidity in Hidradenitis Suppurativa-A Large-Scale Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Reducing non-attendance in hidradenitis suppurativa clinics: insights from a specialty service audit.Irish journal of medical science · 2026Article
- A phenotype-to-mechanism framework links phenome-wide comorbidity architecture to molecular mechanisms and therapeutic discovery in complex diseases.medRxiv : the preprint server for health sciences · 2026Article
- Postmarketing safety of bimekizumab for hidradenitis suppurativa: An early pharmacovigilance analysis using the United States Food and Drug Administration Adverse Event Reporting System.JAAD international · 2026Article
- Presentations of Cutaneous Disease in Various Skin Pigmentations: Hidradenitis Suppurativa.HCA healthcare journal of medicine · 2026Article
- Towards a Paradigm Shift in Delivering Hidradenitis Suppurativa Care: a Narrative Review.Dermatology and therapy · 2025Review
- Cumulative life course impairment: Evidence for hidradenitis suppurativa.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025Review
- Evaluation of eating behaviors in patients with hidradenitis suppurativa: A case-control study.Archives of dermatological research · 2025Article
- Correlation of Psychosomatic Factors and Personality Traits with The Severity of Hidradenitis Suppurativa.Dermatology practical & conceptual · 2025Article
- Multimorbidity of hidradenitis suppurativa: a cross-sectional population-based study of its associated comorbidities.Frontiers in medicine · 2025Article
- Evaluation of the Psychosocial Burden of Hidradenitis Suppurativa and Relevant Factors: A Prospective Single-Center Study.Sisli Etfal Hastanesi tip bulteni · 2025Article
- Demographics, Comorbidity, Treatment, Healthcare Resource Utilization, and Costs Analysis of Hidradenitis Suppurativa in Dubai.Dermatology (Basel, Switzerland) · 2025Article
- Psychiatric Influences on Hidradenitis Suppurativa: A Call for Help.Archives of plastic surgery · 2024Article
- Autoimmune, Autoinflammatory Disease and Cutaneous Malignancy Associations with Hidradenitis Suppurativa: A Cross-Sectional Study.American journal of clinical dermatology · 2024Article
- Demographic features, clinical characteristics, and comorbid relation in hidradenitis suppurativa: a population-based study.Frontiers in medicine · 2024Article
- Unlocking the Mechanisms of Hidradenitis Suppurativa: Inflammation and miRNA Insights.Clinical, cosmetic and investigational dermatology · 2024Review
- Ambulatory palliative care among patients with hidradenitis suppurativa: A qualitative study.JAAD international · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHidradenitis suppurativa (HS) is a chronic inflammatory skin disorder of the hair follicles, and has been associated with a multitude of systemic disorders and pathologies. There is increasing evidence to suggest that chronic inflammatory skin disorders may be associated with psychiatric comorbidities, however this relationship has not been well established. We aimed perform a systematic review and meta-analysis to assess the association between HS and psychiatric comorbidities, suicide and substance abuse.
methodsA systematic review and meta-analysis was performed according to PRISMA guidelines.
resultsHS cases had a significantly higher odds of having schizophrenia compared to the control group (OR 1.66, 95% CI: 1.53-1.79, P<0.00001). There was also a significant association with bipolar disorders (OR 1.96,95% CI: 1.65-2.33, P<0.00001), depression (OR 1.75, 95% CI: 1.44-2.13, P<0.00001), anxiety (OR 1.71, 95% CI: 1.51-1.92, P<0.00001), and personality disorders (OR 1.50, 95% CI: 1.18-1.92, P=0.001), suicide (OR 2.08, 95% CI: 1.27-3.42, P=0.004), substance-related disorders (OR 2.84, 95% CI: 2.33-3.46, P<0.00001), and alcohol abuse (OR 1.94, 95% CI: 1.43-2.64, P<0.0001).
conclusionsFor dermatologists treating patients with HS, screening for these comorbidities, psychiatric referral and adequately managing pain will improve the overall wellbeing of patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.