ReviewFrontiers in veterinary science2020
Current Understanding of the Genetics of Intervertebral Disc Degeneration.
Review in Frontiers in veterinary science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 52 citations in OpenAlex.
- Genotypic Distribution ofGenes · 2026Article
- Dachshund spinal health by coat and size type.Journal of veterinary internal medicine · 2026Article
- Degree of Inflammation in Surgically Obtained Intervertebral Disc Extrusions in a Population of 74 Dogs.Veterinary sciences · 2026Article
- Anatomical Validation and Technical Feasibility of Biportal Endoscopic Spinal Surgery Including Technical Notes in a Cadaveric Canine Thoracic Intervertebral Disc Disease Model.Animals : an open access journal from MDPI · 2026Article
- 3D CT volumetric analysis of spinal canal volume in Bichon Frisé, Dachshund, and French Bulldog: correlation with neurologic severity in thoracolumbar disc herniation.Frontiers in veterinary science · 2026Article
- Article
- Differential gene expression analysis in French bulldog high grade oligodendroglioma: breed-associated differences in tumor and tumor microenvironment gene expression.Companion animal health and genetics · 2025Article
- Allelic frequency of 12-FGF4RG and the association between the genotype with number of calcified intervertebral discs visible on radiographs in Coton de Tuléar and French Bulldog breeds.BMC veterinary research · 2025Article
- Comparison of Clinical Features of Intervertebral Disc Extrusions in English Cocker Spaniels, French Bulldogs and Dachshunds.Animals : an open access journal from MDPI · 2025Article
- Prevalence and breed predisposition for spinal diseases in pugs and French bulldogs.The Veterinary record · 2025Article
- Nano-Drug Delivery System Targeting the Oxidative Stress Microenvironment: A Prospective Strategy for Intervertebral Disc Degeneration Treatment.International journal of nanomedicine · 2025Review
- Causal relationships between dietary factors and spinal diseases: a univariable and multivariable Mendelian randomization study.Frontiers in nutrition · 2025Article
- Post-operative complications following cervical ventral slot in dogs: a retrospective review of the influence of prophylactic fenestration and chondrodystrophy in 593 cases.Frontiers in veterinary science · 2025Article
- Applying the Techniques of Materials Science towards an Understanding of the Process of Canine Intervertebral Disc Degeneration.Animals : an open access journal from MDPI · 2024Article
- A diffusion tensor imaging white matter atlas of the domestic canine brain.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Cervical Disc Extrusion with Dorsal Migration in a Pet Rabbit.Veterinary sciences · 2024Article
- Evaluation of brachycephalic obstructive airway syndrome breeding test results in Finland from 2017 to 2022.Acta veterinaria Scandinavica · 2024Article
- Phillyrin reduces ROS production to alleviate the progression of intervertebral disc degeneration by inhibiting NF-κB pathway.Journal of orthopaedic surgery and research · 2024Article
- Ethical Concerns about Fashionable Dog Breeding.Animals : an open access journal from MDPI · 2024Review
- Prevalence of neurological diseases associated with cervical pain and/or signs of cervical myelopathy in French bulldogs: a retrospective analysis of 105 cases.Frontiers in veterinary science · 2024Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Premature degeneration of the intervertebral disc and its association with specific chondrodystrophic dog breeds has been recognized for over a century. Several lines of evidence including disease breed predisposition, studies suggesting heritability of premature intervertebral disc degeneration (IVDD) and association of a dog chromosome 12 (CFA 12) locus with intervertebral disc calcification have strongly supported a genetic component in IVDD in dogs. Recent studies documenting association of IVDD with an overexpressing
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.