Evidence map›Paper›PMID 32793586›Full record

ArticleFrontiers in cell and developmental biology2020

MicroRNA339 Targeting PDXK Improves Motor Dysfunction and Promotes Neurite Growth in the Remote Cortex Subjected to Spinal Cord Transection.

Liu-Lin Xiong, Yan-Xia Qin, Qiu-Xia Xiao, Yuan Jin, Mohammed Al-Hawwas, Zheng Ma, You-Cui Wang, Visar Belegu, Xin-Fu Zhou, Lu-Lu Xue and 4 more

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  3. Review
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  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 3 countries.

Liu-Lin XiongInstitute of Neurobiological Disease, Department of Anesthesiology, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, China.
Yan-Xia QinDepartment of Histology and Neurobiology, College of Preclinic and Forensic Medicine, Sichuan University, Chengdu, China.
Qiu-Xia XiaoNational Traditional Chinese Medicine Clinical Research Base and Western Medicine Translational Medicine Research Center, Department of Cardiac and Cerebral Diseases, Department of Anesthesiology, Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China.
Yuan JinAnimal Zoology Department, Institute of Neuroscience, Kunming Medical University, Kunming, China.
Mohammed Al-HawwasSchool of Pharmacy and Medical Sciences, Sansom Institute, Division of Health Sciences, University of South Australia, Adelaide, SA, Australia.
Zheng MaAnimal Zoology Department, Institute of Neuroscience, Kunming Medical University, Kunming, China.
You-Cui WangInstitute of Neurobiological Disease, Department of Anesthesiology, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, China.
Visar BeleguInternational Center for Spinal Cord Injury, Kennedy Krieger Institute, Baltimore, MD, United States.
Xin-Fu ZhouSchool of Pharmacy and Medical Sciences, Sansom Institute, Division of Health Sciences, University of South Australia, Adelaide, SA, Australia.
Lu-Lu XueAnimal Zoology Department, Institute of Neuroscience, Kunming Medical University, Kunming, China.
Ruo-Lan DuInstitute of Neurobiological Disease, Department of Anesthesiology, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, China.
Jia LiuAnimal Zoology Department, Institute of Neuroscience, Kunming Medical University, Kunming, China.
Xue BaiNational Traditional Chinese Medicine Clinical Research Base and Western Medicine Translational Medicine Research Center, Department of Cardiac and Cerebral Diseases, Department of Anesthesiology, Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China.
Ting-Hua WangInstitute of Neurobiological Disease, Department of Anesthesiology, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, China.
Kunming Medical University · CNWest China Hospital of Sichuan University · CNSichuan University · CNSouthwest Medical University · CNUniversity of South Australia · AUJohns Hopkins Medicine · US

Funding

Acquisition of GE Typhoon FLA9500 Variable Mode ImagerS10OD021567 · OD · JOHNS HOPKINS UNIVERSITY · PI MCCAFFERY, J. MICHAEL · 2017 to 2017
$147k
NIH HHS S10 OD021567
6 · The paper itself

Abstract

Spinal cord injury (SCI) is a fatal disease that can cause severe disability. Cortical reorganization subserved the recovery of spontaneous function after SCI, although the potential molecular mechanism in this remote control is largely unknown. Therefore, using proteomics analysis, RNA interference/overexpression, and CRISPR/Cas9

Indexed as

microRNA339motor cortex plasticityPDXKRNA interferencespinal cord injury

Identifiers

PMID32793586
PMCPMC7386314
OpenAlexW3044797439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.