Evidence map›Paper›PMID 32793511›Full record

ArticleFrontiers in cellular and infection microbiology2020

Fecal Microbiota Signatures in Celiac Disease Patients With Poly-Autoimmunity.

Stefano Bibbò, Marcello Abbondio, Rosangela Sau, Alessandro Tanca, Giovanna Pira, Alessandra Errigo, Roberto Manetti, Giovanni Mario Pes, Maria Pina Dore, Sergio Uzzau

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Gut microbiota and immunotherapy of renal cell carcinoma.Human vaccines & immunotherapeutics · 2023
    Review
  10. Review
  11. Alopecia Areata: Burden of Disease, Approach to Treatment, and Current Unmet Needs.Clinical, cosmetic and investigational dermatology · 2023
    Review
  12. Article
  13. Gut Dysbiosis and Fecal Microbiota Transplantation in Autoimmune Diseases.International journal of molecular sciences · 2022
    Review
  14. Article
  15. Article
  16. Optimal Thyroid Hormone Replacement.Endocrine reviews · 2022
    Article
  17. Understanding the Gut Microbiota in Pediatric Patients with Alopecia Areata and their Siblings: A Pilot Study.JID innovations : skin science from molecules to population health · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Stefano BibbòDepartment of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.
Marcello AbbondioDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Rosangela SauDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Alessandro TancaDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Giovanna PiraDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Alessandra ErrigoDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Roberto ManettiDepartment of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.
Giovanni Mario PesDepartment of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.
Maria Pina DoreDepartment of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.
Sergio UzzauDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To date, reliable tests enabling the identification of celiac disease (CD) patients at a greater risk of developing poly-autoimmune diseases are not yet available. We therefore aimed to identify non-invasive microbial biomarkers, useful to implement diagnosis of poly-autoimmunity. Twenty CD patients with poly-autoimmunity (cases) and 30 matched subjects affected exclusively by CD (controls) were selected. All patients followed a varied gluten-free diet for at least 1 year. Fecal microbiota composition was characterized using bacterial 16S ribosomal RNA gene sequencing. Significant differences in gut microbiota composition between CD patients with and without poly-autoimmune disease were found using the edgeR algorithm. Spearman correlations between gut microbiota and clinical, demographic, and anthropometric data were also examined. A significant reduction of

Indexed as

Autoimmune DiseasesCeliac DiseaseGastrointestinal MicrobiomeAutoimmunityFecesHumansRNA, Ribosomal, 16SRNA, Ribosomal, 16S16S rRNA gene sequencingceliac diseasegut microbiotametagenomicspoly-autoimmunity

Identifiers

PMID32793511
PMCPMC7390951

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.