Evidence map›Paper›PMID 32793494›Full record

ArticleFrontiers in oncology2020

Inhibition of Sonic Hedgehog Signaling Suppresses Glioma Stem-Like Cells Likely Through Inducing Autophagic Cell Death.

Hui-Chi Hung, Chan-Chuan Liu, Jian-Ying Chuang, Chun-Lin Su, Po-Wu Gean

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

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  14. Radiotherapy and radio-sensitization in H3CNS neuroscience & therapeutics · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Hui-Chi HungDepartment of Pharmacology, College of Medicine, National Cheng-Kung University, Tainan, Taiwan.
Chan-Chuan LiuInstitute of Basic Medical Sciences, College of Medicine, National Cheng-Kung University, Tainan, Taiwan.
Jian-Ying ChuangGraduate Institute of Neural Regenerative Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
Chun-Lin SuDivision of Natural Sciences, Center for General Education, Southern Taiwan University of Science and Technology, Tainan, Taiwan.
Po-Wu GeanDepartment of Pharmacology, College of Medicine, National Cheng-Kung University, Tainan, Taiwan.
National Cheng Kung University · TWInstitute of Basic Medical Sciences of the Chinese Academy of Medical SciencesSouthern Taiwan University of Science and Technology · TWTaipei Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma (GBM) often recurs after radio- and chemotherapies leading to poor prognosis. Glioma stem-like cells (GSCs) contribute to drug resistance and recurrence. Thus, understanding cellular mechanism underlying the growth of GSCs is critical for the treatment of GBM. Here GSCs were isolated from human U87 GBM cells with magnetic-activated cell sorting (MACS) using CD133 as a marker. The CD133

Indexed as

amiodaroneautophagyglioblastomasonic hedgehogstem-like cells

Identifiers

PMID32793494
PMCPMC7393230
OpenAlexW3044832887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.