Evidence map›Paper›PMID 32793464›Full record

ArticleFrontiers in oncology2020

Monitoring of Early Changes of Circulating Tumor DNA in the Plasma of Rectal Cancer Patients Receiving Neoadjuvant Concomitant Chemoradiotherapy: Evaluation for Prognosis and Prediction of Therapeutic Response.

Filip Pazdirek, Marek Minarik, Lucie Benesova, Tereza Halkova, Barbora Belsanova, Milan Macek, Lubomír Stepanek, Jiri Hoch

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05969938 (Predicting the Efficacy and Prognosis of Rectal Cancer Patients Receiving Neoadjuvant Chemoradiotherapy Based on Circulating Tumor DNA-minimal Residual Disease Technology), which is not on this map. Cited by 23 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 4 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05969938 unknown statusnot on this mapstarted 2023, after this paper: background citation

Predicting the Efficacy and Prognosis of Rectal Cancer Patients Receiving Neoadjuvant Chemoradiotherapy Based on Circulating Tumor DNA-minimal Residual Disease Technology : A Prospective, Observational Study

TypeobservationalSponsorWeiWei XiaoRan2023 to 2024Enrolled50ConditionsRectal Adenocarcinoma, Circulating Tumor DNA, Minimal Residual Disease, Neoadjuvant ChemoradiotherapyArmsMRD detection
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Observational
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Filip PazdirekDepartment of Surgery, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czechia.
Marek MinarikDepartment of Surgery, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czechia.
Lucie BenesovaCenter for Applied Genomics of Solid Tumors (CEGES), Genomac Research Institute, Prague, Czechia.
Tereza HalkovaCenter for Applied Genomics of Solid Tumors (CEGES), Genomac Research Institute, Prague, Czechia.
Barbora BelsanovaElphogene, Prague, Czechia.
Milan MacekDepartment of Biology and Medical Genetics, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czechia.
Lubomír StepanekInstitute of Biophysics and Informatics, 1st Faculty of Medicine, Charles University, Prague, Czechia.
Jiri HochDepartment of Surgery, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czechia.
Charles University · CZGenomac · CZUniversity Hospital in Motol · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biomarkercirculating tumor ctDNAneoadjuvant chemoradiotherapypredictionprognosisrectal cancerresponse

Identifiers

PMID32793464
PMCPMC7394215
OpenAlexW3044564192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.