Evidence map›Paper›PMID 32793209›Full record

ArticleFrontiers in immunology2020

Essential Role for CD30-Transglutaminase 2 Axis in Memory Th1 and Th17 Cell Generation.

Akane S Suzuki, Ryoji Yagi, Motoko Y Kimura, Chiaki Iwamura, Kenta Shinoda, Atsushi Onodera, Kiyoshi Hirahara, Damon J Tumes, Ryo Koyama-Nasu, Siiri E Iismaa and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. The Role of Transglutaminase 2 in Cancer: An Update.International journal of molecular sciences · 2024
    Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Akane S SuzukiDepartment of Medical Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Ryoji YagiDepartment of Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Motoko Y KimuraDepartment of Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Chiaki IwamuraDepartment of Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Kenta ShinodaDepartment of Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Atsushi OnoderaDepartment of Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Kiyoshi HiraharaDepartment of Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Damon J TumesDepartment of Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Ryo Koyama-NasuDepartment of Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Siiri E IismaaMolecular Cardiology and Biophysics Division, Victor Chang Cardiac Research Institute, Sydney, NSW, Australia.
Robert M GrahamMolecular Cardiology and Biophysics Division, Victor Chang Cardiac Research Institute, Sydney, NSW, Australia.
Shinichiro MotohashiDepartment of Medical Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Toshinori NakayamaDepartment of Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Chiba University · JPVictor Chang Cardiac Research Institute · AUCentre for Cancer Biology · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Memory helper T (Th) cells are crucial for secondary immune responses against infectious microorganisms but also drive the pathogenesis of chronic inflammatory diseases. Therefore, it is of fundamental importance to understand how memory T cells are generated. However, the molecular mechanisms governing memory Th cell generation remain incompletely understood. Here, we identified CD30 as a molecule heterogeneously expressed on effector Th1 and Th17 cells, and CD30

Indexed as

Immunologic MemoryAdoptive TransferAnimalsCell DifferentiationGTP-Binding ProteinsImmunophenotypingKi-1 AntigenMiceMice, TransgenicProtein Glutamine gamma Glutamyltransferase 2Signal TransductionTh17 CellsTh1 CellsTransglutaminasesGTP-Binding ProteinsKi-1 AntigenProtein Glutamine gamma Glutamyltransferase 2Transglutaminasesairway inflammationCD30memory precursormemory Th cell generationTG2Th1Th17

Identifiers

PMID32793209
PMCPMC7385138
OpenAlexW3042840705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.