Evidence map›Paper›PMID 32793199›Full record

ReviewFrontiers in immunology2020

Targeting Unconventional Host Components for Vaccination-Induced Protection Against TB.

Elisa Nemes, Shabaana A Khader, Rosemary V Swanson, Willem A Hanekom

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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  9. Antigens ofFrontiers in immunology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Elisa NemesSouth African Tuberculosis Vaccine Initiative, Division of Immunology, Department of Pathology and Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Shabaana A KhaderDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, United States.
Rosemary V SwansonDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, United States.
Willem A HanekomAfrica Health Research Institute, Durban, South Africa.
Washington University in St. Louis · USAfrica Health Research Institute · ZAUniversity of Cape Town · ZA

Funding

ROLE OF INDUCIBLE BRONCHUS ASSOCIATED LYMPHOID TISSUE IN LATENT TUBERCULOSISR01AI111914 · NIAID · WASHINGTON UNIVERSITY · PI KAUSHAL, DEEPAK, KHADER, SHABAANA A. · 2015 to 2025
$11.1M
ROLE OF IL-17 IN PROTECTIVE VACCINE-INDUCED IMMUNE RESPONSES AGAINST TUBERCULOSISR01HL105427 · NHLBI · WASHINGTON UNIVERSITY · PI KHADER, SHABAANA A. · 2011 to 2025
$5.9M
The Role of Group 3 Innate Lymphoid cells (ILC3) in TuberculosisR01AI134236 · NIAID · WASHINGTON UNIVERSITY · PI COLONNA, MARCO, KHADER, SHABAANA A. · 2017 to 2021
$4.4M
COMMON IMMUNE CORRELATES OF RISK OF TB DISEASE IN ANIMAL MODELS AND HUMANSR01AI123780 · NIAID · WASHINGTON UNIVERSITY · PI KAUSHAL, DEEPAK, KHADER, SHABAANA A. · 2016 to 2019
$2.9M
NHLBI NIH HHS R01 HL105427NIAID NIH HHS R01 AI111914NIAID NIH HHS R01 AI123780NIAID NIH HHS R01 AI134236
6 · The paper itself

Abstract

The current tuberculosis (TB) vaccine, Bacille Calmette-Guerin (BCG), is effective in preventing TB in young children but was developed without a basic understanding of human immunology. Most modern TB vaccine candidates have targeted CD4

Indexed as

Adaptive ImmunityAnimalsB-LymphocytesHost-Parasite InteractionsHumansImmunity, InnateKiller Cells, NaturalLungMycobacterium tuberculosisTh17 CellsTuberculosisTuberculosis VaccinesTuberculosis VaccinesB cellsNK cellsTh17 Cellstrained immunitytuberculosis

Identifiers

PMID32793199
PMCPMC7393005
OpenAlexW3045334758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.