Evidence map›Paper›PMID 32793194›Full record

ArticleFrontiers in immunology2020

IL-15 and IL15RA in Osteoarthritis: Association With Symptoms and Protease Production, but Not Structural Severity.

Sophie C Warner, Anjali Nair, Rahul Marpadga, Susan Chubinskaya, Michael Doherty, Ana M Valdes, Carla R Scanzello

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 34 citations in OpenAlex.

  1. Exercise-myokine relationships in osteoarthritis.Journal of translational medicine · 2026
    Review
  2. Article
  3. Article
  4. Interleukin 15 and autoimmune disorders: pathophysiology, therapeutic potential, and clinical implications.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Exerkines and osteoarthritis.Frontiers in physiology · 2023
    Review
  17. Article
  18. Article
  19. Article
  20. Adiponectin, May Be a Potential Protective Factor for Obesity-Related Osteoarthritis.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Sophie C WarnerAcademic Rheumatology, Nottingham City Hospital, Nottingham, United Kingdom.
Anjali NairSection of Rheumatology, Rush University Medical Center, Chicago, IL, United States.
Rahul MarpadgaSection of Rheumatology, Rush University Medical Center, Chicago, IL, United States.
Susan ChubinskayaDivision of Pediatrics, Rush University Medical Center, Chicago, IL, United States.
Michael DohertyAcademic Rheumatology, Nottingham City Hospital, Nottingham, United Kingdom.
Ana M ValdesAcademic Rheumatology, Nottingham City Hospital, Nottingham, United Kingdom.
Carla R ScanzelloTranslational Musculoskeletal Research Center & Section of Rheumatology, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, United States.
Rush University Medical Center · USNottingham City Hospital · GBNottingham Biomedical Research Centre · GBPhiladelphia VA Medical Center · US

Funding

INSTITUTIONAL CLINICAL AND TRANSLATIONAL SCIENCE AWARDUL1RR024134 · NCRR · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2006 to 2011
$70.4M
Institutional Clinical and Translational Science AwardUL1TR000003 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2012 to 2015
$38.9M
The Toll-like receptor pathway in Meniscal Injury and OsteoarthritisK08AR057859 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI SCANZELLO, CARLA ROSE · 2010 to 2014
$620k
Meso Scale Discovery Sector 6000 ImagerS10RR026853 · NCRR · CHILDREN'S HOSP OF PHILADELPHIA · PI STANLEY, CHARLES ALFRED · 2010 to 2010
$150k
Arthritis Research UK 18769NCATS NIH HHS UL1 TR000003NCRR NIH HHS S10 RR026853NCRR NIH HHS UL1 RR024134NIAMS NIH HHS K08 AR057859
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

OsteoarthritisAdolescentAdultCartilage, ArticularChondrocytesFemaleHumansInterleukin-15MaleMiddle AgedPainPeptide HydrolasesPolymorphism, Single NucleotideReceptors, Interleukin-15Young AdultIL15 protein, humanIL15RA protein, humanInterleukin-15Peptide HydrolasesReceptors, Interleukin-15inflammationinterleukin-15interleukinsneuropathic painneuropathic pain-like symptomsosteoarthritispainproteases

Identifiers

PMID32793194
PMCPMC7390829
OpenAlexW3043891959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.