Evidence map›Paper›PMID 32792972›Full record

ReviewFrontiers in physiology2020

Methods for Quantifying Neurotransmitter Dynamics in the Living Brain With PET Imaging.

Jenny Ceccarini, Heather Liu, Koen Van Laere, Evan D Morris, Christin Y Sander

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Music engages the phasic dopaminergic D1-receptor system in humans: a PET-fMRI study using [European journal of nuclear medicine and molecular imaging · 2026
    Article
  3. Diversity of words and words for diversity.Frontiers in psychiatry · 2026
    Article
  4. Article
  5. Dynamic Tracking ofMolecular pharmaceutics · 2025
    Article
  6. Brain serotonin, oxytocin, and their interaction: Relevance for eating disorders.Journal of psychopharmacology (Oxford, England) · 2025
    Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Quantitative PET in the 2020s: a roadmap.Physics in medicine and biology · 2021
    Article
  16. Biomedicines · 2021
    Review
  17. The natural axis of transmitter receptor distribution in the human cerebral cortex.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  18. Article
  19. Imaging techniques in drug development.Indian journal of pharmacology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Jenny CeccariniDivision of Nuclear Medicine, University Hospitals Leuven, Leuven, Belgium.
Heather LiuDepartment of Biomedical Engineering, Yale University, New Haven, CT, United States.
Koen Van LaereDivision of Nuclear Medicine, University Hospitals Leuven, Leuven, Belgium.
Evan D MorrisDepartment of Biomedical Engineering, Yale University, New Haven, CT, United States.
Christin Y SanderAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, United States.
KU Leuven · BEHarvard University · USInvicro (United States) · USYale University · US

Funding

Imaging sex differences in smoking-induced dopamine release via novel PET methodsR01DA038709 · NIDA · YALE UNIVERSITY · PI MORRIS, EVAN D · 2015 to 2020
$3.7M
Dopamine-induced PET Occupancy Explored by PET/fMRIR01NS112295 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI MANDEVILLE, JOSEPH B · 2019 to 2023
$2.2M
Imaging dopamine receptor adaptations and signaling pathways with combined PET/fMRI-SupplementR00DA043629 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI SANDER, CHRISTIN Y. · 2019 to 2021
$759k
NIDA NIH HHS R00 DA043629NIDA NIH HHS R01 DA038709NINDS NIH HHS R01 NS112295
6 · The paper itself

Abstract

Positron emission tomography (PET) neuroimaging in neuropsychiatry is a powerful tool for the quantification of molecular brain targets to characterize disease, assess disease subtype differences, evaluate short- and long-term effects of treatments, or even to measure neurotransmitter levels in healthy and psychiatric conditions. In this work, we present different methodological approaches (

Indexed as

brain imaging quantificationdopaminekinetic modelingneurotransmitter releasePET/fMRI

Identifiers

PMID32792972
PMCPMC7385290
OpenAlexW3037455249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.