ArticleContemporary clinical dentistry
Comparative Evaluation of the Remineralizing Potential of Commercially Available Agents on Artificially Demineralized Human Enamel: An
Article in Contemporary clinical dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Biomimetic Strategies for Subsurface Enamel Remineralization: Depth-Dependent Effects of Biomimetic Agents Compared with Fluoride.Biomimetics (Basel, Switzerland) · 2026Article
- Article
- Comparative Evaluation of Remineralization Efficacy of a Novel Proanthocyanidin Biovarnish with Fluoride Varnish on Primary Teeth: AnInternational journal of clinical pediatric dentistry · 2025Article
- A synergistic approach to tooth remineralization using nano-chitosan, fluoride, and pulsed magnetic field.Scientific reports · 2025Article
- Histological effect of fluoride varnishes on teeth with caries in the white spot phase: AnJournal of clinical and experimental dentistry · 2025Article
- Biomimetic remineralization of enamel and dentin with chicken eggshell slurry: AnJournal of conservative dentistry and endodontics · 2025Article
- Systematic Review and Meta-Analysis of Remineralizing Agents: Outcomes on White Spot Lesions.Bioengineering (Basel, Switzerland) · 2025Review
- Comparative Evaluation of Efficacy of Self-Assembling Peptide (P11-4), Bioactive Glass, and Arginine Bicarbonate Remineralizing Agents on Simulated Carious Lesion.Journal of pharmacy & bioallied sciences · 2024Article
- In Vitro Models Used in Cariology Mineralisation Research-A Review of the Literature.Dentistry journal · 2024Review
- Comparative evaluation of remineralization potential of four different remineralization agents on human enamel: AnJournal of conservative dentistry and endodontics · 2024Article
- Effects of Ion-Releasing Materials on Dentine: Analysis of Microhardness, Appearance, and Chemical Composition.Materials (Basel, Switzerland) · 2023Article
- Surface topography and spectrophotometric assessment of white spot lesions restored with nano-hydroxyapatite-containing universal adhesive resin: an in-vitro study.BMC oral health · 2023Article
- A comparative evaluation of the effect of alcoholic and non alcoholic beverages on tooth enamel surface pretreated with β-tricalcium phosphate, bioactive glass and amine fluoride: anMedicine and pharmacy reports · 2023Article
- Nanohydroxyapatite in dentistry: A comprehensive review.The Saudi dental journal · 2023Article
- Potential Beneficial Effects of Hydroxyapatite Nanoparticles on Caries Lesions In Vitro-A Review of the Literature.Dentistry journal · 2023Review
- Remineralizing Potential of Natural Nano-Hydroxyapatite Obtained fromNanomaterials (Basel, Switzerland) · 2022Article
- Comparative Evaluation of Efficacy of Bioactive Glass, Tricalcium Phosphate, and Ozone Remineralizing Agents on Artificial Carious Lesion.Journal of pharmacy & bioallied sciences · 2022Article
- Nano-Hydroxyapatite (nHAp) in the Remineralization of Early Dental Caries: A Scoping Review.International journal of environmental research and public health · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCaries is highly prevalent multifactorial disease, but its progression can be prevented in the initial stage of demineralization through remineralization (RML). Various materials have been proposed for the same, successful outcome can prove to be a boon in the prevention of caries.
aimThe aim of the study is to assess the RML potential of four commercially available agents so as to restore the enamel closest to its previous microhardness levels. MATERIALS AND
methodsSixty permanent intact premolars were randomly divided into six groups: Four test groups - (1) bioactive glass (BAG) Novamin (SHY-NM), (2) nano-hydroxyapatite (nHAp) (Acclaim), (3) functionalized tricalcium phosphate (f-TCP) (Clinpro Tooth Crème), and (4) grape seed extract (GSE); one positive control - (5) fluoride (1000 ppm) containing dentifrice (Colgate Calci-Lock); and one negative control - (6) distilled water. The samples were initially evaluated for baseline surface microhardness (SMH); later on, these samples were placed in the demineralizing solution for 48 h in an incubator at 37°C, and postdemineralization again SMH was measured. Thereafter, the samples were subjected to the pH cycling for consecutive 21 days, and SMH was recorded. The SMH was evaluated using a Vickers microhardness tester. Statistical analysis was done using a
resultsBAG Novamin showed SMH recovery at 96.75% followed by f-TCP at 95.83%, nHAp at 90.88%, and GSE at 48.71%. Statistically significant differences were observed between the first three groups and the rest of the groups after RML stage.
conclusionBAG Novamin, f-TCP, and nHAp showed considerable RML followed to a lesser extent by GSE.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.