Evidence map›Paper›PMID 32792771›Full record

ArticleJournal of cutaneous and aesthetic surgery

Comparative Evaluation of Therapeutic Efficacy of Intralesional Injection of Triamcinolone Acetonide versus Intralesional Autologous Platelet-rich Plasma Injection in Alopecia Areata.

Priya Kapoor, Sumir Kumar, Balvinder K Brar, Neetu Kukar, Hobinder Arora, Sukhmani K Brar

Open access · diamondAbstract read
In one paragraph

Article in Journal of cutaneous and aesthetic surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 4 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. S3 guideline diagnostics and therapy in alopecia areata - Part 2: Therapy, psychosocial and cosmetic support.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026
    Guideline
  2. Treatments for alopecia areata: a network meta-analysis.The Cochrane database of systematic reviews · 2023
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Platelet Rich Plasma and Its Use in Hair Regrowth: A Review.Drug design, development and therapy · 2022
    Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Priya KapoorDepartment of Dermatology, Guru Gobind Singh Medical College and Hospital, Faridkot, India.
Sumir KumarDepartment of Dermatology, Guru Gobind Singh Medical College and Hospital, Faridkot, India.
Balvinder K BrarDepartment of Dermatology, Guru Gobind Singh Medical College and Hospital, Faridkot, India.
Neetu KukarDepartment of Immunohaematology and Blood Transfusion, Guru Gobind Singh Medical College and Hospital, Faridkot, India.
Hobinder AroraDepartment of Community Medicine, Guru Gobind Singh Medical College and Hospital, Faridkot, India.
Sukhmani K BrarDepartment of Dermatology, Adesh Institute of Medical Sciences and Research, Bathinda, Punjab, India.
Guru Gobind Singh Medical College and Hospital · INAdesh University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextAlopecia areata is a chronic non-scarring alopecia that involves scalp and/or body. Corticosteroids are the most popular drugs for its treatment.

aimThe aim of the study was to evaluate the therapeutic efficacy of intralesional injection of triamcinolone acetonide and platelet-rich plasma (PRP) in alopecia areata and to compare the efficacy of these modalities in alopecia areata. SETTINGS AND

designThis was a randomized controlled comparative study. SUBJECTS AND

methodsForty patients were enrolled from the outpatient department and divided into two groups of 20 patients each. Group A and B randomly received intradermal triamcinolone acetonide suspension (10 mg/mL) and PRP, respectively, into the lesion using an insulin syringe in multiple 0.1 mL injections 1cm apart. The injections were repeated every 3 weeks till 12 weeks. The patients were evaluated by Severity of Alopecia Tool (SALT) score and photographically every 3 weeks till the end of 12 weeks and then at the end of 6 months. Statistical analysis used descriptive analysis along with Pearson chi-square test or Fisher exact test, paired samples, and independent samples

resultsThe reduction in SALT score at each visit with respect to baseline was greater in the triamcinolone group as compared to PRP group. This signifies greater effect of triamcinolone in alopecia areata. Around 50% patients in triamcinolone group and 5% patients in PRP group showed grade V improvement. Pain during intralesional injection was higher in the PRP group.

conclusionBoth intralesional triamcinolone and PRP were found to be efficacious in alopecia areata but the latter produced lesser improvement.

Indexed as

Alopecia areataintralesional platelet-rich plasma• Intralesional steroids still remain the first-line drugs for the treatment of patchy alopecia areata.intralesional triamcinolone• PRP does not have direct immunosuppressive action, despite being rich in growth factors.

Identifiers

PMID32792771
PMCPMC7394112
OpenAlexW3047593730

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.