Autologous transplantation of adipose-derived stromal cells combined with sevoflurane ameliorates acute lung injury induced by cecal ligation and puncture in rats.

Zuodi Liang, Heng Zhou, Rurong Tang, Shuo Zhang, Xiaohuan Chen, Ling Pei

Open access · goldAbstract read

In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it

0cells of the map it votes in

4citing papers in PubMed

0.4field-weighted citation impact, top 34% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

From Adipose to Action: Reprogramming Stem Cells for Functional Neural Progenitors for Neural Regenerative Therapy.International journal of molecular sciences · 2025
Review
A nationwide survey on current practices in anesthesia management for lung transplantation in China.Scientific reports · 2025
Article
Topotecan reduces sepsis-induced acute lung injury and decreases the inflammatory response via the inhibition of the NF-κB signaling pathway.Pulmonary circulation · 2022
Article
Mir-204 Regulates LPS-Induced A549 Cell Damage by Targeting FOXK2.Journal of healthcare engineering · 2021
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zuodi LiangAnesthesiology Department, The First Hospital of China Medical University, 155 Nanjing Bei Street, Shenyang, 110001, China.

Heng ZhouAnesthesiology Department, The First Hospital of China Medical University, 155 Nanjing Bei Street, Shenyang, 110001, China.

Rurong TangAnesthesiology Department, The First Hospital of China Medical University, 155 Nanjing Bei Street, Shenyang, 110001, China.

Shuo ZhangAnesthesiology Department, The First Hospital of China Medical University, 155 Nanjing Bei Street, Shenyang, 110001, China.

Xiaohuan ChenAnesthesiology Department, The First Hospital of China Medical University, 155 Nanjing Bei Street, Shenyang, 110001, China.

Ling PeiAnesthesiology Department, The First Hospital of China Medical University, 155 Nanjing Bei Street, Shenyang, 110001, China. LingPei49@sina.com.

First Hospital of China Medical University · CNChina Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adipose-derived stromal cells (ADSCs) have excellent capacities for regeneration and tissue protection, while sevoflurane, as a requisite component of surgical procedures, has shown therapeutic benefit in animal models of sepsis. This study therefore determined if the combination of sevoflurane and ADSCs exerted additional protective effects against acute lung injury (ALI) induced by cecal ligation and puncture (CLP) in rats. The animals were randomized into five groups: (sham operation (group I), CLP followed by mechanical ventilation (group II), CLP plus sevoflurane at 0.5 minimum alveolar concentration (group III), CLP plus intravenous autologous 5 × 10

Indexed as

Mesenchymal Stem Cell TransplantationAcute Lung InjuryAdipose TissueAnimalsBronchoalveolar Lavage FluidCecumCell- and Tissue-Based TherapyCytokinesDisease Models, AnimalEpithelial Sodium ChannelsLigationLungMaleMesenchymal Stem CellsRatsRats, Sprague-DawleyCytokinesEpithelial Sodium ChannelsSevofluraneSodium-Potassium-Exchanging ATPase

Identifiers

PMID32792558

DOI10.3727/096368909X471189

PMCPMC7426944

OpenAlexW3048496240

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.