SynthesisScientific reports2020
Surgical procedures in the pilonidal sinus disease: a systematic review and network meta-analysis.
Synthesis in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 34 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized comparative clinical study between two treatment strategies in patients with pilonidal sinus: conventional care versus negative pressure therapy.
Bilaterally Parallel Elliptic Flap Versus Karydakis Flap in Pilonidal Sinus Disease: A Randomized Controlled Trial
Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 86 citations in OpenAlex.
- Midline and off-midline wound closure methods after surgical treatment for pilonidal sinus.The Cochrane database of systematic reviews · 2024Pooled it
- Laser treatment of pilonidal disease: a systematic review.Lasers in medical science · 2022Pooled it
- A mapping review of sacrococcygeal pilonidal sinus disease.Techniques in coloproctology · 2021Pooled it
- Is it beneficial to add laser ablation to curettage in the treatment of pilonidal sinus disease?Lasers in medical science · 2025Trial
- Effect of sinus resection combined with vacuum-assisted closure on sacrococcygeal pilonidal sinus.International wound journal · 2023Trial
- Bilaterally parallel elliptic flap versus Karydakis flap in primary pilonidal sinus disease: a randomized controlled trial.International journal of colorectal disease · 2023Trial
- Knowledge, attitudes, and practices of hemorrhoid patients regarding surgical treatment.Scientific reports · 2026Article
- An algorithmic proposal for the treatment of pilonidal disease based on outcomes over a 30 year period.Techniques in coloproctology · 2026Article
- Open Pilonidal Excision as a Translational Human Model for Wound Healing and Skin Regeneration Research.Biomedicines · 2026Review
- The New Minimally Invasive Techniques for Pilonidal Sinus Disease Surgery: Choosing the Right Technique for the Right Patient-A Narrative Review.Medicina (Kaunas, Lithuania) · 2026Review
- Advancing pilonidal disease care through pediatric endoscopic treatment (PEPSiT): early insights.Pediatric surgery international · 2026Article
- Limberg flap reconstruction for recurrent pilonidal sinus disease: A single-center U.S. Cohort.Langenbeck's archives of surgery · 2026Article
- Kiss Y flap: a novel low-tension reconstruction technique after excision of pilonidal sinus.Gastroenterology report · 2026Article
- Pilonidal sinus disease prevalence and risk factors in Saudi Arabia: A cross-sectional study.Journal of family medicine and primary care · 2026Article
- Article
- Comparative analysis of treatment modalities and contributing factors in recurrent pilonidal sinus disease.Experimental and therapeutic medicine · 2025Article
- Future of pilonidal cyst surgery: a comparative review of traditional and laser techniques.BMC surgery · 2025Review
- Long term results and quality of life after primary excision followed by Limberg plasty in pilonidal sinus disease.Langenbeck's archives of surgery · 2025Article
- Comparative Outcomes of Surgical Techniques for Pilonidal Sinus: A Turkish Retrospective Study.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Karydakis Flap as a Simple Surgical Method in the Treatment of Pilonidal Disease V.S Open Surgery with Average 30-month-follow up: A Clinical Trial.Medical journal of the Islamic Republic of Iran · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The most appropriate surgical treatment for pilonidal sinus disease (PSD) is still in dispute. This study aims to comprehensively compare the outcomes of surgical interventions using network meta-analysis. Randomized controlled trial studies were searched systematically to identify all eligible studies in multiple databases and previous publications and Bayesian network meta-analysis was performed. Our primary outcome was the recurrence rate. Differences in the findings of the studies were explored in meta regressions and sensitivity analyses. The risk of bias of each study was assessed using the Cochrane risk of bias tool. Confidence in evidence was assessed using CINeMA (Confidence in Network Meta-Analysis). A total of 39 studies and 5,061 patients were identified and the most common surgical intervention was the Limberg flap. In network meta-analysis, modified Limberg flap and off-midline closure were associated with the lowest recurrence rate. However, the Karydakis flap was associated with shorter operation time by several minutes compared with other interventions and few significant results were found in other outcomes. Modified Limberg flap and off-midline closure provided relatively low recurrence and complications rates. Therefore, they could be two promising surgical interventions for PSD patients.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.