Evidence map›Paper›PMID 32792507›Full record

ArticleScientific reports2020

CINENet: deep learning-based 3D cardiac CINE MRI reconstruction with multi-coil complex-valued 4D spatio-temporal convolutions.

Thomas Küstner, Niccolo Fuin, Kerstin Hammernik, Aurelien Bustin, Haikun Qi, Reza Hajhosseiny, Pier Giorgio Masci, Radhouene Neji, Daniel Rueckert, René M Botnar and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed, 1 pooled it
14.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 1 synthesis or guideline pooled it, 231 citations in OpenAlex.

  1. Pooled it
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  18. Measuring biventricular function and left atrial volume in a single five-dimensional whole-heart cardiovascular magnetic resonance scan at 0.55T.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
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  19. Review
  20. Clinical feasibility of two cardiac deep learning cine magnetic resonance imaging sequences: Single-breath-hold and free-breathing motion-corrected approaches.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Article

29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Thomas KüstnerSchool of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, Lambeth Wing, London, UK. thomas.kuestner@kcl.ac.uk.
Niccolo FuinSchool of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, Lambeth Wing, London, UK.
Kerstin HammernikDepartment of Computing, Imperial College London, London, UK.
Aurelien BustinSchool of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, Lambeth Wing, London, UK.
Haikun QiSchool of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, Lambeth Wing, London, UK.
Reza HajhosseinySchool of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, Lambeth Wing, London, UK.
Pier Giorgio MasciSchool of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, Lambeth Wing, London, UK.
Radhouene NejiSchool of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, Lambeth Wing, London, UK.
Daniel RueckertDepartment of Computing, Imperial College London, London, UK.
René M BotnarSchool of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, Lambeth Wing, London, UK.
Claudia PrietoSchool of Biomedical Engineering and Imaging Sciences, King's College London, St. Thomas' Hospital, Lambeth Wing, London, UK.
King's College London · GBImperial College London · GBPontificia Universidad Católica de Chile · CLSiemens (United Kingdom) · GBSt Thomas' Hospital · GB

Funding

British Heart Foundation RG/20/1/34802
6 · The paper itself

Abstract

Cardiac CINE magnetic resonance imaging is the gold-standard for the assessment of cardiac function. Imaging accelerations have shown to enable 3D CINE with left ventricular (LV) coverage in a single breath-hold. However, 3D imaging remains limited to anisotropic resolution and long reconstruction times. Recently deep learning has shown promising results for computationally efficient reconstructions of highly accelerated 2D CINE imaging. In this work, we propose a novel 4D (3D + time) deep learning-based reconstruction network, termed 4D CINENet, for prospectively undersampled 3D Cartesian CINE imaging. CINENet is based on (3 + 1)D complex-valued spatio-temporal convolutions and multi-coil data processing. We trained and evaluated the proposed CINENet on in-house acquired 3D CINE data of 20 healthy subjects and 15 patients with suspected cardiovascular disease. The proposed CINENet network outperforms iterative reconstructions in visual image quality and contrast (+ 67% improvement). We found good agreement in LV function (bias ± 95% confidence) in terms of end-systolic volume (0 ± 3.3 ml), end-diastolic volume (- 0.4 ± 2.0 ml) and ejection fraction (0.1 ± 3.2%) compared to clinical gold-standard 2D CINE, enabling single breath-hold isotropic 3D CINE in less than 10 s scan and ~ 5 s reconstruction time.

Indexed as

Deep LearningSpatio-Temporal AnalysisAdultBreath HoldingCardiovascular DiseasesCase-Control StudiesFemaleHumansImage Interpretation, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance Imaging, CineMaleMiddle AgedProspective Studies

Identifiers

PMID32792507
PMCPMC7426830
OpenAlexW3048384642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.