ArticleBMJ global health2020
An analysis of clinical predictive values for radiographic pneumonia in children.
Article in BMJ global health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Diagnostic accuracy of tachypnoea for predicting mortality and identifying sepsis in young infants aged 0-59 days: a systematic review and meta-analysis.BMJ paediatrics open · 2026Pooled it
- Trial
- Innovative, enhanced community management of non-hypoxaemic chest-indrawing pneumonia in 2-59-month-old children: a cluster-randomised trial in Africa and Asia.BMJ global health · 2022Trial
- Integrating Local and Global Representation Learning for Pediatric Pneumonia Detection: A Hybrid CNN-Transformer Ensemble Framework.Diagnostics (Basel, Switzerland) · 2026Article
- Lung ultrasound combined with C-reactive protein for identifying a bacterial component in children hospitalized with acute lower respiratory tract infections: a prospective observational study.European journal of pediatrics · 2026Observational
- Digital stethoscope use by non-physician primary care health workers on children under five years of age in rural Bangladesh: a feasibility study.Scientific reports · 2026Article
- Clinician Assessment for Acute Chest Syndrome in Febrile Children With Sickle Cell Disease Revisited.American journal of hematology · 2026Article
- Chest Radiography Use in Hospitalized Children with Acute Respiratory Tract Infections: A Baseline Analysis for Imaging Optimization.Children (Basel, Switzerland) · 2026Article
- Use of radiograph scoring systems to assess pulmonary disease severity in patients with COVID-19 pneumonia.World journal of critical care medicine · 2026Article
- Recent updates regarding the management and treatment of pneumonia in pediatric patients: a comprehensive review.Infection · 2025Review
- ePOCT+ Rwanda: A Clinical Decision Support Algorithm For Managing Sick Children Below 15 Years of Age in Primary Healthcare Settings.Rwanda journal of medicine and health sciences · 2025Article
- Article
- Clinical Implications of the Obstructive Pattern on Chest Radiography in Children Aged 3-59 Months With Severe Lower Respiratory Tract Infections.Pediatric pulmonology · 2025Article
- Accuracy of Lung Ultrasound Compared to Chest Radiography for Diagnosing Pneumonia in Children: A Hospital-Based Cross-Sectional Study.Ethiopian journal of health sciences · 2024Article
- Clinicopathological discrepancies in the diagnoses of childhood causes of death in the CHAMPS network: An analysis of antemortem diagnostic inaccuracies.BMJ paediatrics open · 2024Article
- Work of Breathing: Physiology, Measurement, and Diagnostic Value in Childhood Pneumonia.Children (Basel, Switzerland) · 2024Review
- Article
- Pathogenic Role and Antibiotic Resistance of Methicillin-ResistantAdvances in respiratory medicine · 2023Article
- Health System Considerations for Community-Based Implementation of Automated Respiratory Counters to Identify Childhood Pneumonia in 5 Regions of Ethiopia: A Qualitative Study.International journal of health policy and management · 2023Article
- Antibiotic resistance ofFrontiers in public health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 14 institutions in 11 countries.
Funding
Abstract
introductionHealthcare providers in resource-limited settings rely on the presence of tachypnoea and chest indrawing to establish a diagnosis of pneumonia in children. We aimed to determine the test characteristics of commonly assessed signs and symptoms for the radiographic diagnosis of pneumonia in children 0-59 months of age.
methodsWe conducted an analysis using patient-level pooled data from 41 shared datasets of paediatric pneumonia. We included hospital-based studies in which >80% of children had chest radiography performed. Primary endpoint pneumonia (presence of dense opacity occupying a portion or entire lobe of the lung or presence of pleural effusion on chest radiograph) was used as the reference criterion radiographic standard. We assessed the sensitivity, specificity, and likelihood ratios for clinical findings, and combinations of findings, for the diagnosis of primary endpoint pneumonia among children 0-59 months of age.
resultsTen studies met inclusion criteria comprising 15 029 children; 24.9% (n=3743) had radiographic pneumonia. The presence of age-based tachypnoea demonstrated a sensitivity of 0.92 and a specificity of 0.22 while lower chest indrawing revealed a sensitivity of 0.74 and specificity of 0.15 for the diagnosis of radiographic pneumonia. The sensitivity and specificity for oxygen saturation <90% was 0.40 and 0.67, respectively, and was 0.17 and 0.88 for oxygen saturation <85%. Specificity was improved when individual clinical factors such as tachypnoea, fever and hypoxaemia were combined, however, the sensitivity was lower.
conclusionsNo single sign or symptom was strongly associated with radiographic primary end point pneumonia in children. Performance characteristics were improved by combining individual signs and symptoms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.