ArticleCanadian journal of diabetes2020
Depression in Girls With Obesity and Polycystic Ovary Syndrome and/or Type 2 Diabetes.
Article in Canadian journal of diabetes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Depression comorbidity in children and adolescents with type 2 diabetes mellitus: a systematic review and meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Depression, anxiety and self-esteem in adolescent girls with polycystic ovary syndrome: a systematic review and meta-analysis.Frontiers in endocrinology · 2024Pooled it
- Treatment and complications of PCOS in adolescents - what's new in 2023?Frontiers in endocrinology · 2024Pooled it
- Prevalence of Polycystic Ovary Syndrome in Patients With Pediatric Type 2 Diabetes: A Systematic Review and Meta-analysis.JAMA network open · 2022Pooled it
- Depressive symptoms in adolescents with and without polycystic ovary syndrome living with obesity: a case-control study.Reproductive biology and endocrinology : RB&E · 2025Observational
- Obesity Management in Female Adolescents.Clinical endocrinology · 2025Review
- International evidence-based recommendations for polycystic ovary syndrome in adolescents.BMC medicine · 2025Review
- Comprehensive transition of care for polycystic ovary syndrome from adolescence to adulthood.The Lancet. Child & adolescent health · 2024Review
- Association between mild depressive states in polycystic ovary syndrome and an unhealthy lifestyle.Frontiers in public health · 2024Article
- Prevalence and associated risk factors for depression symptoms in adolescent girls with polycystic ovary syndrome: a hospital-based cross-sectional study.Frontiers in public health · 2024Article
- Criteria for Diagnosis of Polycystic Ovary Syndrome during Adolescence: Literature Review.Diagnostics (Basel, Switzerland) · 2022Review
- Measurement Invariance of the GAD-7 and CESD-R-10 Among Adolescents in Canada.Journal of pediatric psychology · 2022Article
- Care for Adolescents With Polycystic Ovary Syndrome: Development and Prescribing Patterns of a Multidisciplinary Clinic.Journal of pediatric and adolescent gynecology · 2021Article
- Weight Management in Adolescents with Polycystic Ovary Syndrome.Current obesity reports · 2021Review
- "CoVidentary": An online exercise training program to reduce sedentary behaviours in children with type 1 diabetes during the COVID-19 pandemic.Journal of clinical & translational endocrinology · 2021Article
- Mental Health in Diabetes: Never a Better Time.Canadian journal of diabetes · 2020Article
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesPolycystic ovary syndrome (PCOS) is a common reproductive/metabolic condition associated with obesity, type 2 diabetes (T2D) and depression in adult women. Depression in adults is related to PCOS dermatologic manifestations. Adolescents with obesity with or without T2D have elevated depression symptoms, but data from youth with PCOS and obesity with/without T2D are limited.
methodsOur study included girls, aged 11 to 17 years, with obesity and PCOS, PCOS+T2D or T2D, who were newly seen in an obesity complications clinic after March 2016. All participants had Center for Epidemiologic Studies-Depression (CES-D, 20 items) scores obtained within 6 months of PCOS or T2D diagnosis. Data on history of psychiatric diagnosis and treatment, metabolic syndrome and severity of acne and hirsutism were collected through chart review.
resultsOne hundred five girls (47 with PCOS, 14 with PCOS+T2D, 44 with T2D) had similar age (15±1.8 years) and body mass index z scores (2.2±0.4). CES-D scores ≥16, indicating elevated depression symptoms, and CES-D scores ≥24, indicating severe depression symptoms, were observed in 60% and 30% of girls with PCOS, 78% and 71% of those with PCOS+T2D and 39% and 21% of those with T2D, respectively (p<0.0001 for both cutpoints). A higher CES-D score was not associated with severity of hirsutism or acne (p>0.05 for both).
conclusionsAdolescents with PCOS and obesity have higher rates of elevated depression symptoms compared with girls with T2D, which is not related to worse dermatologic symptoms. Because depression may impact both PCOS and T2D management and adherence to therapy, greater efforts should be made to screen for and address mental health in adolescents with PCOS and obesity, especially if T2D is present.
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