Evidence map›Paper›PMID 32791885›Full record

ArticleThyroid : official journal of the American Thyroid Association2021

The Intrinsic Activity of Thyroxine Is Critical for Survival and Growth and Regulates Gene Expression in Neonatal Liver.

Valerie Anne Galton, Maria Elena Martinez, Julie A Dragon, Donald L St Germain, Arturo Hernandez

Open access · greenAbstract readComparative Study
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Primary hypothyroidism and quality of life.Nature reviews. Endocrinology · 2022
    Review
  4. Optimal Thyroid Hormone Replacement.Endocrine reviews · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Valerie Anne GaltonDepartment of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Maria Elena MartinezMaine Medical Center Research Institute, MaineHealth, Scarborough, Maine, USA.
Julie A DragonDepartment of Microbiology and Molecular Genetics, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA.
Donald L St GermainMaine Medical Center Research Institute, MaineHealth, Scarborough, Maine, USA.
Arturo HernandezMaine Medical Center Research Institute, MaineHealth, Scarborough, Maine, USA.
MaineHealth · USDartmouth College · USTufts University · USUniversity of Vermont · US

Funding

Understanding Factors Influencing COVID-19 Testing and Vaccination in Immigrant Low-income and Homeless Populations and Testing Targeted InterventionsU54GM115516 · NIGMS · MAINEHEALTH · PI CLIFFORD JAMES ROSEN · 2017 to 2026
$51.6M
Progenitor Cell Analysis CoreP30GM106391 · NIGMS · MAINEHEALTH · PI FRIESEL, ROBERT E · 2013 to 2017
$5.7M
Transgenerational Epigenetic Programming of the Thyroid AxisR01DK095908 · NIDDK · MAINEHEALTH · PI Arturo Hernandez · 2012 to 2026
$5.1M
NIDDK NIH HHS R01 DK095908NIGMS NIH HHS P30 GM106391NIGMS NIH HHS U54 GM115516
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Age FactorsAnimalsAnimals, NewbornCholesterolFemaleGene Expression ProfilingGene Expression Regulation, DevelopmentalIodide PeroxidaseIodothyronine Deiodinase Type IILiverMaleMiceMice, KnockoutPAX8 Transcription FactorRNA-SeqThyroxineCholesterolIodide PeroxidaseIodothyronine Deiodinase Type IIPax8 protein, mousePAX8 Transcription Factorselenodeiodinase type 1, mouseThyroxineTriiodothyroninecholesterolgrowthsurvivalthyroid hormonethyroxinetranscription

Identifiers

PMID32791885
PMCPMC7994419
OpenAlexW3049249496

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.