Evidence map›Paper›PMID 32791843›Full record

ReviewCirculation. Cardiovascular imaging2020

Disentangling the Links Between Psychosocial Stress and Cardiovascular Disease.

Michael T Osborne, Lisa M Shin, Nehal N Mehta, Roger K Pitman, Zahi A Fayad, Ahmed Tawakol

Abstract readReview
In one paragraph

Review in Circulation. Cardiovascular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 181 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
181citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

181 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Article
  8. Gender diversity and cholesterol in early adolescence: Findings from the Adolescent Brain Cognitive Development Study.International journal of cardiology. Cardiovascular risk and prevention · 2026
    Article
  9. Chronic Stress and Cardiovascular Health: The MESA and MASALA Studies.American journal of preventive medicine · 2026
    Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Glucose as a Biomarker for Stress in Firefighters.Journal of occupational and environmental medicine · 2026
    Article
  20. Article

121 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael T OsborneCardiology Division (M.T.O., A.T.), Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Lisa M ShinDepartment of Psychiatry (L.M.S., R.K.P.), Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Nehal N MehtaSection of Inflammation and Cardiometabolic Diseases, National Heart, Lung, and Blood Institute, Bethesda, MD (N.N.M.).
Roger K PitmanDepartment of Psychiatry (L.M.S., R.K.P.), Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Zahi A FayadBiomedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (Z.A.F.).
Ahmed TawakolCardiology Division (M.T.O., A.T.), Massachusetts General Hospital and Harvard Medical School, Boston, MA.

Funding

Translational imaging and nanomedicine in inflammatory atherosclerosisP01HL131478 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Zahi A. Fayad · 2017 to 2026
$24.3M
Institutional Career Development CoreKL2TR002542 · NCATS · HARVARD MEDICAL SCHOOL · PI BREDELLA, MIRIAM ANTOINETTE, RUTKOVE, SEWARD B. · 2018 to 2022
$8.7M
Atherosclerosis in cocaine addiction: imaging risk with PET/MRR01DA049547 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Nelly Alia-Klein, Zahi A. Fayad · 2022 to 2026
$3.9M
Novel PET/CT and Treatment Strategies to reduce PTS following DVTR01HL137913 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI JAFFER, FAROUC AMIN, TAWAKOL, AHMED A · 2017 to 2020
$3.3M
Effect of PCSK9 Inhibition on Cardiovascular Risk in Treated HIV Infection (EPIC-HIV Study)R33HL141047 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HSUE, PRISCILLA Y., LU, MICHAEL TSE-YIN · 2019 to 2022
$2.9M
Effect of PCSK9 Inhibition on Cardiovascular Risk in Treated HIV Infection (EPIC-HIV Study)R61HL141047 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HOFFMANN, UDO, HSUE, PRISCILLA Y. · 2018 to 2018
$730k
NCATS NIH HHS KL2 TR002542NHLBI NIH HHS P01 HL131478NHLBI NIH HHS R01 HL137913NHLBI NIH HHS R33 HL141047NHLBI NIH HHS R61 HL141047NIDA NIH HHS R01 DA049547
6 · The paper itself

Abstract

Stress is a pervasive component of the human experience. While often considered an adversity to be ignored, chronic stress has important pathological consequences, including cardiovascular disease (CVD). Stress also increases the prevalence and severity of several CVD risk factors, including hypertension, diabetes mellitus, and obesity. Yet even after adjustment, stress' attributable CVD risk is similar to those risk factors, suggesting it is a particularly potent contributor. Nevertheless, there has been insufficient study of mechanisms linking stress to CVD or of methods to attenuate stress' pathological impact. This review covers the current concepts of how stress impacts CVD and emerging approaches to mitigate stress-attributable CVD risk.

Indexed as

Cardiovascular DiseasesStress, PsychologicalAnimalsBrainCardiovascular SystemHeart Disease Risk FactorsHumansPrevalencePrognosisRisk Assessmentatherosclerosiscardiovascular diseaseshumanshypertensionpsychological distressrisk adjustmentrisk factors

Identifiers

PMID32791843
PMCPMC7430065

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.