ArticleEuropean journal of dentistry2020
In Vitro Whitening Effect of a Hydroxyapatite-Based Oral Care Gel.
Article in European journal of dentistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- Caries-preventing effect of a hydroxyapatite-toothpaste in adults: a 18-month double-blinded randomized clinical trial.Frontiers in public health · 2023Trial
- Antimicrobial and Antibiofilm Properties of Hydroxyapatite/Nano-Hydroxyapatite in Preventing Dental Caries: A Systematic Review.European journal of dentistry · 2025Article
- Review
- Influence of the Amount of Toothpaste on Cleaning Efficacy: An In Vitro Study.European journal of dentistry · 2023Article
- Remineralization Strategies for Teeth with Molar Incisor Hypomineralization (MIH): A Literature Review.Dentistry journal · 2023Review
- Tooth Whitening with Hydroxyapatite: A Systematic Review.Dentistry journal · 2023Review
- Effectiveness and Safety of Over-the-Counter Tooth-Whitening Agents Compared to Hydrogen Peroxide In Vitro.International journal of molecular sciences · 2023Article
- Article
- Incorporation of Fluoride into Human Teeth after Immersion in Fluoride-Containing Solutions.Dentistry journal · 2022Article
- Tooth whitening with an experimental toothpaste containing hydroxyapatite nanoparticles.BMC oral health · 2022Article
- The use of hydroxyapatite toothpaste to prevent dental caries.Odontology · 2022Review
- Adhesion and whitening efficacy of P11-4 self-assembling peptide and HAP suspension after using NaOCl as a pre-treatment agent.BMC oral health · 2022Article
- The Use of Calcium Phosphates in Cosmetics, State of the Art and Future Perspectives.Materials (Basel, Switzerland) · 2021Review
- Effects of charcoal-based whitening toothpastes on human enamel in terms of color, surface roughness, and microhardness: an in vitro study.Clinical oral investigations · 2021Article
- Hydroxyapatite in Oral Care Products-A Review.Materials (Basel, Switzerland) · 2021Review
- Cariogenic Biofilms: Development, Properties, and Biomimetic Preventive Agents.Dentistry journal · 2021Review
- Whitening Effects of a Novel Oral Care Gel with Biomimetic Hydroxyapatite: A 4-Week Observational Pilot Study.Biomimetics (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveOral care formulations aim to prevent oral diseases such as dental caries and gingivitis. Additionally, desire for white teeth still exists across all age groups. It is known that most whitening toothpastes are highly abrasive and can be harmful to teeth and gingiva. Therefore, a gel formulation with biomimetic hydroxyapatite (HAP; Ca MATERIALS AND
methodsEnamel samples were allocated to either group (a) HAP gel, (b) whitening mouth rinse with phosphates, or (c) negative control (distilled water). Test products were applied by finger (a) or were rinsed (b, c) for 1, 3, and 9 (b and c only) cycles, respectively.
resultsColor changes (ΔE) were measured spectrophotometrically. Group (a) showed a significant increase in color changes with respect to whitening after one cycle (mean ΔE = 5.4 [±2.66],
conclusionThis
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.