ArticleMolecular biology and evolution2021
Amoeba Genome Reveals Dominant Host Contribution to Plastid Endosymbiosis.
Article in Molecular biology and evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 34 citations in OpenAlex.
- Evidence of Relaxed Selection in the Mitochondrial Genomes of Phototrophic Paulinella Lineages.Genome biology and evolution · 2026Article
- Evolution of molecular communication in the permanent Azolla symbiosis.The New phytologist · 2026Review
- The Paulinella chromatophore transit peptide part2 adopts a structural fold similar to the γ-glutamyl-cyclotransferase fold.Plant physiology · 2025Article
- Genomes of nitrogen-fixing eukaryotes reveal an alternate path for organellogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Protein import into bacterial endosymbionts and evolving organelles.The FEBS journal · 2025Review
- Evidence of a putative COEnvironmental microbiology reports · 2024Article
- The consequences of viral infection on protists.Communications biology · 2024Review
- Diurnal Rhythms in the Red Seaweed Gracilariopsis chorda are Characterized by Unique Regulatory Networks of Carbon Metabolism.Molecular biology and evolution · 2024Article
- DNA-binding and protein structure of nuclear factors likely acting in genetic information processing in theProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Large-scale invasion of unicellular eukaryotic genomes by integrating DNA viruses.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Phycobilisomes and Phycobiliproteins in the Pigment Apparatus of Oxygenic Photosynthetics: From Cyanobacteria to Tertiary Endosymbiosis.International journal of molecular sciences · 2023Review
- Three-dimensional architecture and assembly mechanism of the egg-shaped shell in testate amoebaFrontiers in cell and developmental biology · 2023Article
- Loss of key endosymbiont genes may facilitate early host control of the chromatophore iniScience · 2022Article
- Tracking N-terminal protein processing from the Golgi to the chromatophore of a rhizarian amoeba.Plant physiology · 2022Article
- Retrotransposition facilitated the establishment of a primary plastid in the thecate amoebaProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Hypothesis: Trans-splicing Generates Evolutionary Novelty in the Photosynthetic Amoeba Paulinella.Journal of phycology · 2022Article
- A bipartite chromatophore transit peptide and N-terminal protein processing in the Paulinella chromatophore.Plant physiology · 2022Article
- Why is primary endosymbiosis so rare?The New phytologist · 2021Review
- Independent evolution of the thioredoxin system in photosynthetic Paulinella species.Current biology : CB · 2021Article
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Authors and funding
13 authors at 4 institutions in 3 countries.
Funding
Abstract
Eukaryotic photosynthetic organelles, plastids, are the powerhouses of many aquatic and terrestrial ecosystems. The canonical plastid in algae and plants originated >1 Ga and therefore offers limited insights into the initial stages of organelle evolution. To address this issue, we focus here on the photosynthetic amoeba Paulinella micropora strain KR01 (hereafter, KR01) that underwent a more recent (∼124 Ma) primary endosymbiosis, resulting in a photosynthetic organelle termed the chromatophore. Analysis of genomic and transcriptomic data resulted in a high-quality draft assembly of size 707 Mb and 32,361 predicted gene models. A total of 291 chromatophore-targeted proteins were predicted in silico, 208 of which comprise the ancestral organelle proteome in photosynthetic Paulinella species with functions, among others, in nucleotide metabolism and oxidative stress response. Gene coexpression analysis identified networks containing known high light stress response genes as well as a variety of genes of unknown function ("dark" genes). We characterized diurnally rhythmic genes in this species and found that over 49% are dark. It was recently hypothesized that large double-stranded DNA viruses may have driven gene transfer to the nucleus in Paulinella and facilitated endosymbiosis. Our analyses do not support this idea, but rather suggest that these viruses in the KR01 and closely related P. micropora MYN1 genomes resulted from a more recent invasion.
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