Evidence map›Paper›PMID 32790622›Full record

ArticleeLife2020

Atypical meiosis can be adaptive in outcrossed

María Angélica Bravo Núñez, Ibrahim M Sabbarini, Lauren E Eide, Robert L Unckless, Sarah E Zanders

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Proliferation and dissemination of killer meiotic drive loci.Current opinion in genetics & development · 2023
    Review
  6. Article
  7. TheeLife · 2022
    Article
  8. Article
  9. Molecular Mechanisms and Evolutionary Consequences of Spore Killers in Ascomycetes.Microbiology and molecular biology reviews : MMBR · 2021
    Review
  10. Article
  11. TheeLife · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

María Angélica Bravo NúñezStowers Institute for Medical Research, Kansas City, United States.ORCID 0000-0002-6554-8814
Ibrahim M SabbariniStowers Institute for Medical Research, Kansas City, United States.ORCID 0000-0001-6490-7056
Lauren E EideStowers Institute for Medical Research, Kansas City, United States.
Robert L UncklessDepartment of Molecular Biosciences, University of Kansas, Lawrence, United States.ORCID 0000-0001-8586-7137
Sarah E ZandersStowers Institute for Medical Research, Kansas City, United States.ORCID 0000-0003-1867-986X
Stowers Institute for Medical Research · USUniversity of Kansas · US

Funding

Models of Selfishness: Molecular and Evolutionary Analyses of the Wtf Meiotic DriversDP2GM132936 · NIGMS · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI ZANDERS, SARAH ELIZABETH · 2018 to 2018
$2.5M
Mechanisms of meiotic drive and the functional consequences of rapid genome evolutionR00GM114436 · NIGMS · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI ZANDERS, SARAH ELIZABETH · 2016 to 2018
$747k
Conflict-driven aneuploidy and genomic instability caused by meiotic proteinsK00CA234523 · NCI · HARVARD UNIVERSITY · PI BRAVO NUNEZ, MARIA ANGELICA · 2020 to 2020
$86k
Conflict-driven aneuploidy and genomic instability caused by meiotic proteinsF99CA234523 · NCI · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI BRAVO NUNEZ, MARIA ANGELICA · 2018 to 2019
$59k
Kinship Foundation Searle Scholars AwardMarch of Dimes Foundation Basil O'Connor Starter Scholar Research Award No. 5-FY18-58NCI NIH HHS F99 CA234523NCI NIH HHS F99CA234523NCI NIH HHS K00 CA234523NIGMS NIH HHS DP2 GM132936NIGMS NIH HHS DP2GM132936NIGMS NIH HHS R00 GM114436NIGMS NIH HHS R00GM114436
6 · The paper itself

Abstract

Killer meiotic drivers are genetic parasites that destroy 'sibling' gametes lacking the driver allele. The fitness costs of drive can lead to selection of unlinked suppressors. This suppression could involve evolutionary tradeoffs that compromise gametogenesis and contribute to infertility.

Indexed as

Genes, FungalGene Expression Regulation, FungalMeiosisSchizosaccharomycesSchizosaccharomyces pombe ProteinsSpores, FungalSchizosaccharomyces pombe Proteinsaneuploidychromosome segregationevolutionary biologygeneticsgenomicsinfertilitymeiosismeiotic driveS. pombewtf

Identifiers

PMID32790622
PMCPMC7426094
OpenAlexW3048944824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.