Evidence map›Paper›PMID 32789763›Full record

ArticleForensic science, medicine, and pathology2021

Signet-ring cell appearance of atrophic fat cells.

John D Gilbert, Neil E I Langlois, Andrew Ruszkiewicz, David Moffat, Kathy Cash

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Forensic science, medicine, and pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Gelatinous transformation of bone marrow in a rabbit.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2021
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

John D GilbertForensic Science SA, GPO Box 2790, Adelaide, South Australia, 5001, Australia.
Neil E I LangloisForensic Science SA, GPO Box 2790, Adelaide, South Australia, 5001, Australia. Neil.Langlois@sa.gov.au.
Andrew RuszkiewiczSchool of Medical and Health Sciences, University of Adelaide, Adelaide, South Australia, Australia.
David MoffatAnatomical Pathology, SA Pathology, Flinders Medical Centre, Bedford Park, South Australia.
Kathy CashAnatomical Pathology, SA Pathology, Frome Rd, Adelaide, South Australia, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cells with 'signet-ring' appearance were found at post-mortem examination of a man with a history of chronic illness, weight loss and multiple regions of 'bowel thickening' during life. Due to the decedent's history, the finding raised the possibility of disseminated signet-ring adenocarcinoma. However, the vacuoles did not stain for mucin and the cells did not stain for keratin. The cells did stain for calretinin and so a diagnosis of signet ring mesothelioma was considered. However, it was suggested that the cells with a cytoplasmic vacuole displacing the nucleus to one side producing the signet-ring appearance were instead atrophic fat cells. This was subsequently proven by Oil Red O staining.

Indexed as

AdipocytesAtrophyCarcinoma, Signet Ring CellCytoplasmDiagnosis, DifferentialHumansMaleMesotheliomaMiddle AgedStaining and LabelingVacuolesAdipocyteAutopsyCachexiaDiagnostic errorsFrozen sectionSignet ring cell

Identifiers

PMID32789763

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.