Evidence map›Paper›PMID 32789546›Full record

ArticleDrug delivery and translational research2020

Intranasal administration of budesonide-loaded nanocapsule microagglomerates as an innovative strategy for asthma treatment.

Manoel Ortiz, Diego de Sa Coutinho, Bianca Torres Ciambarella, Everton Tenorio de Souza, Ana Paula Leite D'Almeida, Taís Lusa Durli, Patrícia Machado Rodrigues E Silva, Andressa Bernardi, Fabio Sonvico, Adriana Raffin Pohlmann and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Drug delivery and translational research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Nanotechnology-Based Therapeutics for Airway Inflammatory Diseases.Clinical reviews in allergy & immunology · 2025
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Manoel OrtizPrograma de Pós-Graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga 2752, Porto Alegre, 90610-000, Brazil.
Diego de Sa CoutinhoLaboratório de Inflamação, Instituto Oswaldo Cruz, FIOCRUZ, Av. Brasil, 4365, Rio de Janeiro, 21040-360, Brazil.
Bianca Torres CiambarellaLaboratório de Inflamação, Instituto Oswaldo Cruz, FIOCRUZ, Av. Brasil, 4365, Rio de Janeiro, 21040-360, Brazil.
Everton Tenorio de SouzaLaboratório de Inflamação, Instituto Oswaldo Cruz, FIOCRUZ, Av. Brasil, 4365, Rio de Janeiro, 21040-360, Brazil.
Ana Paula Leite D'AlmeidaLaboratório de Inflamação, Instituto Oswaldo Cruz, FIOCRUZ, Av. Brasil, 4365, Rio de Janeiro, 21040-360, Brazil.
Taís Lusa DurliPrograma de Pós-Graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga 2752, Porto Alegre, 90610-000, Brazil.
Patrícia Machado Rodrigues E SilvaLaboratório de Inflamação, Instituto Oswaldo Cruz, FIOCRUZ, Av. Brasil, 4365, Rio de Janeiro, 21040-360, Brazil.
Andressa BernardiLaboratório de Inflamação, Instituto Oswaldo Cruz, FIOCRUZ, Av. Brasil, 4365, Rio de Janeiro, 21040-360, Brazil.
Fabio SonvicoDipartimento di Scienze degli Alimenti e del Farmaco, Università degli studi di Parma, Parco Area delle Scienze, 27/A, 43124, Parma, Italy.
Adriana Raffin PohlmannPrograma de Pós-Graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga 2752, Porto Alegre, 90610-000, Brazil.ORCID 0000-0001-5222-1807
Marco Aurelio MartinsLaboratório de Inflamação, Instituto Oswaldo Cruz, FIOCRUZ, Av. Brasil, 4365, Rio de Janeiro, 21040-360, Brazil. mmartins@ioc.fiocruz.br.
Sílvia Stanisçuaski GuterresPrograma de Pós-Graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga 2752, Porto Alegre, 90610-000, Brazil. silvia.guterres@ufrgs.br.ORCID 0000-0002-6085-6826
Fundação Oswaldo Cruz · BRUniversidade Federal do Rio Grande do Sul · BRUniversity of Parma · IT

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 465687/2014-8FAPESP 2014/50928-2Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul 16/2551-0000467-6
6 · The paper itself

Abstract

The co-existence with rhinitis limits the control of asthma. Compared with oral H

Indexed as

AsthmaNanocapsulesAdministration, IntranasalAdrenal Cortex HormonesAnimalsBudesonideMaleMiceAdrenal Cortex HormonesBudesonideNanocapsulesAsthmaBronchoalveolar lavage fluidBudesonideCytokinesEotaxin-1Lung histologyPolymeric nanocapsulesSpray-drying

Identifiers

PMID32789546
OpenAlexW3048647633

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.