Evidence map›Paper›PMID 32789541›Full record

Observational studyEuropean journal of pediatrics2021

Plethysmography variability index (PVI) changes in preterm neonates with shock-an observational study.

Dinesh Pawale, Srinivas Murki, Dattatray Kulkarni, Venkateshwarlu Vardhelli, Deepak Sharma, Tejopratap Oleti, Sai Kiran, Venkat Kallem, Tanveer Bashir

Abstract readObservational Study
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In one paragraph

Observational study in European journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Monitoring and evaluation of hypotension in the extremely preterm.Frontiers in cardiovascular medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Dinesh PawaleDepartment of Neonatology, Fernandez Hospital, Hyderabad, Telangana, India. dinesh_pawale@rediffmail.com.ORCID http://orcid.org/0000-0001-7876-6936
Srinivas MurkiDepartment of Neonatology, Fernandez Hospital, Hyderabad, Telangana, India.
Dattatray KulkarniDepartment of Neonatology, Fernandez Hospital, Hyderabad, Telangana, India.
Venkateshwarlu VardhelliDepartment of Neonatology, Fernandez Hospital, Hyderabad, Telangana, India.
Deepak SharmaDepartment of Neonatology, Fernandez Hospital, Hyderabad, Telangana, India.
Tejopratap OletiDepartment of Neonatology, Fernandez Hospital, Hyderabad, Telangana, India.
Sai KiranDepartment of Neonatology, Fernandez Hospital, Hyderabad, Telangana, India.
Venkat KallemDepartment of Neonatology, Fernandez Hospital, Hyderabad, Telangana, India.
Tanveer BashirDepartment of Neonatology, Fernandez Hospital, Hyderabad, Telangana, India.
Fernandez Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shock is an acute state of circulatory dysfunction. The diagnosis of shock is complex in neonates. The relative sensitivity of current clinical or laboratory findings for detecting shock is largely unknown, especially for preterm neonates. For preload assessment, inferior vena cava (IVC) collapsibility can be a useful bedside echocardiography parameter. plethysmography variability index (PVI) is a marker of fluid responsive shock in adults and children, but not well defined in neonates. In this prospective observational study, we evaluated the changes in PVI in preterm neonates with shock. Among the 37 infants enrolled in the study, the mean blood pressure (MAP) was 45 (± 4 mm of Hg) and none of infants had hypotension. The mean pulse pressure was 28 mm of Hg, the mean PVI was 28% (±5), the mean arterial blood gas pH was 7.20 (±0.07), and the mean base deficit was 9.9 (±2.53) at the onset of shock. Thirty (96.77%) of the 31 infants with resolution of shock showed decrease in PVI with an average decrease of 11% (±5).Conclusion: Significant proportion of neonates show an increase in PVI at the onset of shock. What is Known: • Plethysmography Variability Index (PVI) is commonly used as a marker of volume status in paediatric population. • Changes in PVI may guide in giving volume boluses in patients with shock. What is New: • This study provides information of changes in PVI in preterm neonates with shock. • PVI may become a valuable tool to be used at bedside in preterm infants with shock.

Indexed as

HypotensionShockBlood PressureFluid TherapyHumansInfantInfant, NewbornInfant, PrematurePlethysmographyVena Cava, InferiorIVC collapsibility indexPVIShockVolume status

Identifiers

PMID32789541
OpenAlexW3048740161

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.