Evidence map›Paper›PMID 32789534›Full record

ReviewParasitology research2020

Granulomas in parasitic diseases: the good and the bad.

Selma Giorgio, Pedro Henrique Gallo-Francisco, Guilherme Augusto Sanches Roque, Marina Flóro E Silva

Abstract readReview
PubMed Publisher
In one paragraph

Review in Parasitology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
0.3field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Characterization of Transcriptional, Epigenetic, and Phenotypic Plasticity and Discovery of Biomarkers in Acute and Chronic Murine Schistosomiasis Infection.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  8. Schistosoma mansoni Infection in Three Green Monkeys (Chlorocebus sabaeus) Originating from Saint Kitts.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
    Article
  9. Article
  10. Differential murine responses toInfection and immunity · 2024
    Article
  11. Immune response to viscerotropicFrontiers in immunology · 2024
    Review
  12. Review
  13. Review
  14. A Partially Protective Vaccine forAnimals : an open access journal from MDPI · 2021
    Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Selma GiorgioDepartment of Animal Biology, Biology Institute, State University of Campinas, Campinas, 13083-865, Brazil. sgiorgio@unicamp.br.ORCID https://orcid.org/0000-0002-5685-9661
Pedro Henrique Gallo-FranciscoDepartment of Animal Biology, Biology Institute, State University of Campinas, Campinas, 13083-865, Brazil.
Guilherme Augusto Sanches RoqueDepartment of Animal Biology, Biology Institute, State University of Campinas, Campinas, 13083-865, Brazil.
Marina Flóro E SilvaDepartment of Animal Biology, Biology Institute, State University of Campinas, Campinas, 13083-865, Brazil.
Universidade Estadual de Campinas (UNICAMP) · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 405581/2018-1Fundação de Amparo à Pesquisa do Estado de São Paulo 2018/23302-6
6 · The paper itself

Abstract

Parasitic diseases affect more than one billion people worldwide, and most of them are chronic conditions in which the treatment and prevention are difficult. The appearance of granulomas, defined as organized and compact structures of macrophages and other immune cells, during various parasitic diseases is frequent, since these structures will only form when individual immune cells do not control the invading agent. Th2-typering various parasitic diseases are frequent, since these structures will only form when individual immune cells do not control the invading agent. The characterization of granulomas in different parasitic diseases, as well as recent findings in this field, is discussed in this review, in order to understand the significance of the granuloma and its modulation in the host-parasite interaction and in the immune, pathological, and parasitological aspects of this interaction. The parasitic granulomatous diseases granulomatous amebic encephalitis, toxoplasmosis, leishmaniasis, neurocysticercosis, and schistosomiasis mansoni are discussed as well as the mechanistic and dynamical aspects of the infectious granulomas.

Indexed as

AnimalsGranulomaHost-Parasite InteractionsHumansMacrophagesNeurocysticercosisSchistosoma mansoniSchistosomiasis mansoniTaenia soliumToxoplasmaToxoplasmosisGranulomaGranulomatous amebic encephalitisLeishmaniasisNeurocysticercosisSchistosomiasis mansoniToxoplasmosis

Identifiers

PMID32789534
OpenAlexW3048468156

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.