ArticleContemporary clinical trials communications2020
COVID-19 disparities: An urgent call for race reporting and representation in clinical research.
Article in Contemporary clinical trials communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sex, Racial, and Ethnic Representation in COVID-19 Clinical Trials: A Systematic Review and Meta-analysis.JAMA internal medicine · 2023Pooled it
- Convalescent Plasma for Preventing Critical Illness in COVID-19: a Phase 2 Trial and Immune Profile.Microbiology spectrum · 2022Trial
- Racial and Ethnic Representation Reporting in Orthopaedic Research.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026Article
- The influence of socioeconomic status on individual attitudes and experience with clinical trials.Communications medicine · 2024Article
- Challenging assumptions about the demographics of eosinophilic gastrointestinal diseases: A systematic review.The journal of allergy and clinical immunology. Global · 2024Article
- Analysis of eligibility criteria in Alzheimer's and related dementias clinical trials.Scientific reports · 2024Article
- Mapping Strategies for Reaching Socioeconomically Disadvantaged Populations in Clinical Trials.JAMA network open · 2024Article
- Racial and ethnic diversity in global neuroscience clinical trials.Contemporary clinical trials communications · 2024Article
- Effective interventions to increase representation of under-served groups in randomised trials in UK and Ireland: a scoping literature review.NIHR open research · 2024Article
- Assessing Unique Risk Factors for COVID-19 Complications Among Cancer Patients: A Multi-ethnic Cohort Study.Journal of immigrant and minority health · 2023Article
- Evaluating Demographic Representation in Clinical Trials: Use of the Adaptive Coronavirus Disease 2019 Treatment Trial (ACTT) as a Test Case.Open forum infectious diseases · 2023Article
- We still cannot breathe: Applying intersectional ecological model to COVID-19 survivorship.Rehabilitation psychology · 2023Review
- Association of Glucose-6-Phosphate Dehydrogenase Deficiency With Outcomes in US Veterans With COVID-19.JAMA network open · 2023Article
- Enablers and barriers to engaging under-served groups in research: Survey of the United Kingdom research professional's views.NIHR open research · 2023Article
- A Framework for Interfacing and Partnering with Environmental Justice Communities as a Prelude to Human Health and Hazard Identification in the Vulnerable Census Tracts of Columbus, Ohio.International journal of environmental research and public health · 2022Review
- To Address Women's Health Inequity, It Must First Be Measured.Health equity · 2022Article
- Racial and ethnic variation in COVID-19 care, treatment, and outcomes: A retrospective cohort study from the MiCOVID-19 registry.PloS one · 2022Article
- Characteristics and Factors Associated With Coronavirus Disease 2019 Infection, Hospitalization, and Mortality Across Race and Ethnicity.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Lesbian, Gay, Bisexual, Transgender, and Queer (LGBTQ+) Communities and the Coronavirus Disease 2019 Pandemic: A Call to Break the Cycle of Structural Barriers.The Journal of infectious diseases · 2021Article
- The effectiveness of visual triaging and testing of suspected COVID-19 cases in primary care setting in Saudi Arabia.Journal of family medicine and primary care · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRacial/ethnic disparities in disease burden have gained the spotlight in the United States with the spread of SARS-CoV-2 and surge of COVID-19 cases. The problem of underrepresentation in clinical research persists today. In light of the considerable COVID-19 disparities observed, this study sought to assess the race reporting and representation among COVID-19 therapeutic studies published to date.
methodsAll published COVID-19 treatment-related clinical research studies with study participants in the United States were identified. For each study, the date published, treatment investigated, study design, race/ethnicity of participants, sample size and study site were recorded. For each study site, the race/ethnicity demographics of confirmed COVID-19 positive cases were identified utilizing online publicly available department of public health data.
resultsSix studies (n = 3, observational; n = 3, randomized clinical trial) have been published to date with participants in the United States. A subset (n = 4) reported race/ethnicity data in the publication. Black patients were underrepresented in all studies relative to the affected population in the cities in which the studies took place.
conclusionsGiven that racial/ethnic disparities in COVID-19 disease burden and outcomes have emerged in the United States, it is essential that all investigators uniformly report race/ethnicity data as well as attempt, in earnest, to obtain representativeness among study participants in order to ensure that we do not develop a further widening of the treatment gap during this pandemic.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.