Evidence map›Paper›PMID 32789268›Full record

ArticleProgress in rehabilitation medicine2019

Risk Factors for Lymphedema in Breast Cancer Survivors Following Axillary Lymph Node Dissection.

Yoshiteru Akezaki, Ritsuko Tominaga, Masato Kikuuchi, Hideaki Kurokawa, Makiko Hamada, Kenjiro Aogi, Shozo Ohsumi, Tetsuya Tsuji, Susumu Kawamura, Shinsuke Sugihara

Open access · diamondAbstract read
In one paragraph

Article in Progress in rehabilitation medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Association between chemotherapy and the risk of developing breast cancer-related lymphedema: a nationwide retrospective cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yoshiteru AkezakiDivision of Physical Therapy, Kochi Professional University of Rehabilitation, Kochi, Japan.
Ritsuko TominagaDepartment of Rehabilitation Medicine, National Hospital Organization Shikoku Cancer Center, Ehime, Japan.
Masato KikuuchiDepartment of Rehabilitation Medicine, National Hospital Organization Shikoku Cancer Center, Ehime, Japan.
Hideaki KurokawaDepartment of Rehabilitation Medicine, National Hospital Organization Shikoku Cancer Center, Ehime, Japan.
Makiko HamadaDepartment of Rehabilitation Medicine, National Hospital Organization Shikoku Cancer Center, Ehime, Japan.
Kenjiro AogiDepartment of Breast Surgery, National Hospital Organization Shikoku Cancer Center, Ehime, Japan.
Shozo OhsumiDepartment of Breast Surgery, National Hospital Organization Shikoku Cancer Center, Ehime, Japan.
Tetsuya TsujiDepartment of Rehabilitation Medicine, Keio University Hospital, Tokyo, Japan.
Susumu KawamuraDepartment of Plastic and Reconstructive Surgery, National Hospital Organization Shikoku Cancer Center, Ehime, Japan.
Shinsuke SugiharaDepartment of Rehabilitation Medicine, National Hospital Organization Shikoku Cancer Center, Ehime, Japan.
Shikoku Cancer Center · JPKeio University Hospital · JPKochi Rehabilitation Institute · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of the current study was to assess the risk factors for developing lymphedema following breast cancer treatment.

methodsThe subjects of this study were 238 consecutive patients who underwent axillary lymph node dissection for breast cancer at Shikoku Cancer Center. The study variables were the occurrence of lymphedema, the body mass index, the follow-up period, the drain removal time, the level of lymph node dissection, the presence or absence of co-resident household members, radiation therapy, neoadjuvant chemotherapy, and adjuvant chemotherapy.

resultsWe observed lymphedema in 23.9% of patients after axillary lymph node dissection for breast cancer. Neoadjuvant chemotherapy and adjuvant chemotherapy using docetaxel and cyclophosphamide increased the risk of developing lymphedema (P <0.05).

conclusionsThose patients treated with neoadjuvant chemotherapy and adjuvant chemotherapy using docetaxel and cyclophosphamide should be observed closely after axillary lymph node dissection, and appropriate intervention should be considered from an early stage.

Indexed as

axillary lymph node dissectionbreast cancerchemotherapylymphedemaupper limb

Identifiers

PMID32789268
PMCPMC7365249
OpenAlexW2991068431

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.