Evidence map›Paper›PMID 32789192›Full record

ArticleWellcome open research2020

Large CRISPR-Cas-induced deletions in the oxamniquine resistance locus of the human parasite

Geetha Sankaranarayanan, Avril Coghlan, Patrick Driguez, Magda E Lotkowska, Mandy Sanders, Nancy Holroyd, Alan Tracey, Matthew Berriman, Gabriel Rinaldi

Open access · goldAbstract read
In one paragraph

Article in Wellcome open research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Chemical inhibition of α-mannosidase inFrontiers in parasitology · 2026
    Article
  3. Review
  4. Review
  5. Applications of CRISPR in Parasitology.Current pharmaceutical biotechnology · 2025
    Review
  6. Review
  7. Review
  8. Transmission-Blocking Vaccines against Schistosomiasis Japonica.International journal of molecular sciences · 2024
    Review
  9. Review
  10. Trematode Genomics and Proteomics.Advances in experimental medicine and biology · 2024
    Article
  11. Schistosomiasis.Advances in experimental medicine and biology · 2024
    Review
  12. Article
  13. Article
  14. Gene editing in the nematode parasiteFrontiers in parasitology · 2023
    Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 3 countries.

Geetha Sankaranarayanan *Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.
Avril Coghlan *Wellcome Sanger Institute, Hinxton, CB10 1SA, UK.ORCID https://orcid.org/0000-0002-2775-5951
Patrick DriguezWellcome Sanger Institute, Hinxton, CB10 1SA, UK.ORCID https://orcid.org/0000-0001-8104-677X
Magda E LotkowskaWellcome Sanger Institute, Hinxton, CB10 1SA, UK.
Mandy SandersWellcome Sanger Institute, Hinxton, CB10 1SA, UK.
Nancy HolroydWellcome Sanger Institute, Hinxton, CB10 1SA, UK.
Alan TraceyWellcome Sanger Institute, Hinxton, CB10 1SA, UK.ORCID https://orcid.org/0000-0002-4805-9058
Matthew BerrimanWellcome Sanger Institute, Hinxton, CB10 1SA, UK.ORCID https://orcid.org/0000-0002-9581-0377
Gabriel RinaldiWellcome Sanger Institute, Hinxton, CB10 1SA, UK.ORCID https://orcid.org/0000-0002-7767-4922
Tufts University · US

Funding

Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Amplicon sequencingCRISPR-Cas9CRISPRessoGenome editingSchistosoma mansoniSulfotransferaseTransfectionTransgenesis

Identifiers

PMID32789192
PMCPMC7405262.2
OpenAlexW3044854198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.