Evidence map›Paper›PMID 32789148›Full record

ArticleClinical nutrition research2020

Association between Inflammatory Biomarkers and Nutritional Status in Fatty Liver.

Hee-Sook Lim, Joungyun Choi, Bora Lee, Sang Gyune Kim, Young Seok Kim, Jeong-Ju Yoo

Open access · diamondAbstract read
In one paragraph

Article in Clinical nutrition research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Hee-Sook LimDepartment of Food Sciences & Nutrition, Yeonsung University, Anyang 14011, Korea.ORCID https://orcid.org/0000-0003-0745-8906
Joungyun ChoiDepartment of Health and Nutrition Survey, Korean Centers for Disease Control & Prevention, Cheongju 28159, Korea.ORCID https://orcid.org/0000-0002-3471-6782
Bora LeeDepartment of Biostatistics, Graduate School of Chung-Ang University, Seoul 06974, Korea.ORCID https://orcid.org/0000-0002-6322-5712
Sang Gyune KimDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon 14854, Korea.ORCID https://orcid.org/0000-0001-8694-777X
Young Seok KimDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon 14854, Korea.ORCID https://orcid.org/0000-0002-7113-3623
Jeong-Ju YooDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon 14854, Korea.ORCID https://orcid.org/0000-0002-7802-0381
Soonchunhyang University · KRChung-Ang University · KRKorea Center for Disease Control and Prevention · KRYeonsung University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence and progression of non-alcoholic fatty liver disease (NAFLD) is mediated via several factors correlating with hepatic necroinflammation (adipokines/cytokines). This study was performed to analyze the level of inflammatory markers according to the presence of NAFLD and to identify related nutritional factors. A total of 80 adults were classified into 2 groups (healthy and NAFLD), and their body composition, blood tests, and eating habits were evaluated. In addition, inflammatory markers (adiponectin, high-sensitivity C-reactive protein [CRP], and tumor necrosis factor-alpha [TNF-α]), nutrient intake status, and dietary quality were compared. The quality of diet was assessed according to the nutrient adequacy ratio and the mean adequacy ratio (MAR). The NAFLD group had a higher body mass index (p < 0.001) than the healthy group and also carried significantly higher CRP levels (p < 0.001) but lower adiponectin (p = 0.001). TNF-α levels increased significantly with fatty liver grade (p = 0.023). The NAFLD group showed significantly higher intake of energy, carbohydrates, iron, sodium, vitamin A and saturated fatty acids, but significantly lower intake of zinc and vitamin E than the healthy group. The MAR values were slightly higher in the NAFLD group but without any significant difference. The levels of adiponectin and vitamin E showed a significant inverse correlation (p < 0.05). Nutritional management of NAFLD patients is important, and the intake of antioxidant and anti-inflammatory nutrients such as zinc and vitamin E should be emphasized.

Indexed as

AdipokinesAdiponectinNon-alcoholic fatty liver diseaseNutrientsVitamin E

Identifiers

PMID32789148
PMCPMC7402975
OpenAlexW3046586107

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.