ArticleEuropean journal of case reports in internal medicine2020
Takotsubo Cardiomyopathy Due to Combined Use of Phentermine and Lisdexamfetamine.
Article in European journal of case reports in internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 authors at 1 institution in 1 country.
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Abstract
objectivesThis is the first case report of iatrogenic Takotsubo syndrome (TS) due to a combination of lisdexamfetamine and phentermine.
backgroundTS is characterized by transient acute ballooning of the left ventricular wall. Typically, it occurs in extremely stressed post-menopausal women, however a few iatrogenic causes have been described recently.
resultsA 55-year old woman prescribed lisdexamfetamine and phentermine, presented with acute substernal chest pain. Acute coronary syndrome was excluded. The echocardiogram was diagnostic of TS, and she recovered spontaneously, with supportive care.
conclusionCaution with the use of sympathomimetic medications in post-menopausal women appears warranted. LEARNING POINTS: This is the first case report in the published English literature of medication-induced Takotsubo cardiomyopathy due to combination use of lisdexamfetamine and phentermine.This provides new information about iatrogenic causes of Takotsubo cardiomyopathy.Caution is indicated in the use of such medications, particularly in post-menopausal women, who are at higher risk.
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