Evidence map›Paper›PMID 32788916›Full record

ArticleThe journal of venomous animals and toxins including tropical diseases2020

Anna Beatriz R Mayor, Leonardo A Guevarra, Myla R Santiago-Bautista, Librado A Santiago

Open access · goldAbstract read
In one paragraph

Article in The journal of venomous animals and toxins including tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. A venom fraction from the Philippine tarantula (The journal of venomous animals and toxins including tropical diseases · 2026
    Article
  3. Neuroactive venom compounds obtained fromThe journal of venomous animals and toxins including tropical diseases · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anna Beatriz R MayorThe Graduate School, University of Santo Tomas, Manila, Philippines.ORCID 0000-0002-2256-1357
Leonardo A GuevarraResearch Center for Natural and Applied Sciences, University of Santo Tomas, Manila, Philippines.
Myla R Santiago-BautistaThe Graduate School, University of Santo Tomas, Manila, Philippines.
Librado A SantiagoThe Graduate School, University of Santo Tomas, Manila, Philippines.
University of Santo Tomas · PH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSpider venom is a potential source of pharmacologically important compounds. Previous studies on spider venoms reported the presence of bioactive molecules that possess cell-modulating activities. Despite these claims, sparse scientific evidence is available on the cytotoxic mechanisms in relation to the components of the spider venom. In this study, we aimed to determine the cytotoxic fractions of the spider venom extracted from

methodsSpider venom was extracted by electrostimulation. Components of the extracted venom were separated by reversed-phase high performance liquid chromatography (RP-HPLC) using a linear gradient of 0.1% trifluoroacetic acid (TFA) in water and 0.1% TFA in 95% acetonitrile (ACN). Cytotoxic activity was evaluated by the MTT assay. Apoptotic or necrotic cell death was assessed by microscopic evaluation in the presence of Hoechst 33342 and Annexin V, Alexa Fluor

resultsWe observed and isolated six fractions from the venom of

conclusionThe venom of

Indexed as

CytotoxicityHuman lung adenocarcinomaPhilippine spidersPhlogiellus bundokalboSpider venom

Identifiers

PMID32788916
PMCPMC7401667
OpenAlexW3048030482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.