ArticleScientific reports2020
Tobamoviruses can be frequently present in the oropharynx and gut of infants during their first year of life.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 25 citations in OpenAlex.
- Shotgun metagenomic sequencing and genetic characterization of four enteric viruses in a dairy farm suffering a diarrhea outbreak of undetermined cause in adult cattle.Archives of virology · 2026Article
- Antiviral activity and mechanism of purine morpholine nucleoside analogues incorporating a sulfonamide fragment.Journal of advanced research · 2026Article
- Plant Virus Intratumoral Immunotherapy with CPMV and PVX Elicits Durable Antitumor Immunity in a Mouse Model of Diffuse Large B-Cell Lymphoma.Molecular pharmaceutics · 2024Article
- Alterations of the gut microbiome in HIV infection highlight human anelloviruses as potential predictors of immune recovery.Microbiome · 2024Article
- Longitudinal analysis of the enteric virome in paediatric subjects from the Free State Province, South Africa, reveals early gut colonisation and temporal dynamics.Virus research · 2024Article
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- Exploring the Human Virome: Composition, Dynamics, and Implications for Health and Disease.Current microbiology · 2023Review
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- Pepper Mild Mottle Virus: An Infectious Pathogen in Pepper Production and a Potential Indicator of Domestic Water Quality.Viruses · 2023Review
- The fecal and oropharyngeal eukaryotic viromes of healthy infants during the first year of life are personal.Scientific reports · 2023Article
- Tomato brown rugose fruit virus in aqueous environments - survival and significance of water-mediated transmission.Frontiers in plant science · 2023Article
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- Role of pepper mild mottle virus as a tracking tool for fecal pollution in aquatic environments.Archives of microbiology · 2022Review
- Monitoring SARS-CoV-2 in the Wastewater and Rivers of Tapachula, a Migratory Hub in Southern Mexico.Food and environmental virology · 2022Article
- High Prevalence and Diversity of Caliciviruses in a Community Setting Determined by a Metagenomic Approach.Microbiology spectrum · 2022Article
- Risk perception associated with an emerging agri-food risk in Europe: plant viruses in agriculture.Agriculture & food security · 2022Article
- No Evidence Known Viruses Play a Role in the Pathogenesis of Onchocerciasis-Associated Epilepsy. An Explorative Metagenomic Case-Control Study.Pathogens (Basel, Switzerland) · 2021Article
- The gut virome of healthy children during the first year of life is diverse and dynamic.PloS one · 2021Article
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant viruses have been reported to be common in the gut of human adults, presumably as result of food ingestion. In this work, we report that plant viruses can also be found frequently in the gut and oropharynx of children during their first year of life, even when they are exclusively breast-fed. Fecal and oropharynx samples were collected monthly, from birth to 1 year of age, from three apparently healthy children in a semi-rural community and analyzed by next generation sequencing. In 100% of the fecal samples and 65% of the oropharynx samples at least one plant virus was identified. Tobamoviruses in the Virgaviridae family were by far the most frequently detected, with tropical soda apple mosaic virus, pepper mild mottle virus, and opuntia tobamovirus 2 being the most common species. Seventeen complete virus genomes could be assembled, and phylogenetic analyses showed a large diversity of virus strains circulating in the population. These results suggest that children are continuously exposed to an extensive and highly diverse collection of tobamoviruses. Whether the common presence of plant viruses at an early age influences the infant's immune system, either directly or through interaction with other members of the microbiota, remains to be investigated.
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