Evidence map›Paper›PMID 32788671›Full record

ArticleScientific reports2020

Risk factors for the deterioration of periventricular-intraventricular hemorrhage in preterm infants.

Tian Wu, Yan Wang, Tao Xiong, Sheng Huang, Tian Tian, Jun Tang, Dezhi Mu

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Development of a machine learning model for prediction of intraventricular hemorrhage in premature neonates.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Article
  6. Article
  7. Risk factors associated with intraventricular hemorrhage in very-low-birth-weight premature infants.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Hemangioma-related gene polymorphisms in the pathogenesis of intraventricular hemorrhage in preterm infants.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
    Article
  12. Article
  13. Article
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  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tian Wu *Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.
Yan Wang *Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.
Tao XiongDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China. tao_xiong@126.com.ORCID http://orcid.org/0000-0002-0408-1288
Sheng HuangDepartment of Information Management, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Tian TianDepartment of Epidemiology and Biostatistics, School of Public Health, Institute of Reproductive and Child Health, Peking University Health Science Center, Beijing, China.
Jun TangDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.
Dezhi MuDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preterm infants with periventricular-intraventricular hemorrhage (PV-IVH) have a high risk of neurological sequelae, with severity depending on the severity of the PV-IVH. Previous studies on the pathogenesis of PV-IVH have focused mainly on comparisons of perinatal risk factors between patients with and without PV-IVH. Notably, most cases of PV-IVH occur within the first 3 days after birth, and the condition may worsen within 1 week following the initial diagnosis. However, the risk factors that contribute to the deterioration of PV-IVH have not been investigated. In this cohort study, 514 PV-IVH infants with a gestational age (GA) < 32 weeks were enrolled. The dependent variable was initially diagnosed as mild PV-IVH (grade I or II) that subsequently progressed to severe PV-IVH (grade III or IV) within 1 week. A stepwise forward multivariate logistic regression model was adopted to select potential or related factors that affected the deterioration of PV-IVH in preterm infants. Overall, 42 of the 514 infants with PV-IVH (8.2%) showed deterioration within 1 week. The results showed that maternal lower genital tract infection (OR 3.73, 95% CI 1.75-7.95) was an independent risk factor for PV-IVH deterioration. Higher GA (OR 0.62, 95% CI 0.48-0.80) was a protective factor. Our results suggest that maternal lower genital tract infection and a lower GA may contribute to PV-IVH deterioration in preterm infants.

Indexed as

Cerebral HemorrhageCohort StudiesFemaleGestational AgeHumansInfantInfant, PrematureInfant, Premature, DiseasesLogistic ModelsMaleMultivariate AnalysisPrognosisRetrospective StudiesRisk FactorsSeverity of Illness Index

Identifiers

PMID32788671
PMCPMC7423930

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.