ArticleJournal of perinatology : official journal of the California Perinatal Association2020
Zinc deficiency limiting head growth to discharge in extremely low gestational age infants with insufficient linear growth: a cohort study.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
- Clinical biochemical evaluation of trace elements and insulin-like growth factor-I in children with short stature: Diagnostic and correlative insights from the Guangzhou cohort.Journal of medical biochemistry · 2026Article
- Improved linear growth after routine zinc supplementation in preterm very low birth weight infants.Pediatric research · 2025Article
- A validated NICU database: recounting 50 years of clinical growth, quality improvement and research.Pediatric research · 2025Article
- The role of zinc in the premature brain: functions, outcomes and future research perspectives.Frontiers in pediatrics · 2024Review
- Improving growth in preterm infants through nutrition: a practical overview.Frontiers in nutrition · 2024Review
- Dynamic Interplay between Social Brain Development and Nutrient Intake in Young Children.Nutrients · 2023Article
- Growth after implementing a donor breast milk program in neonates <33 weeks gestational age or birthweight <1500 grams: Retrospective cohort study.Journal of perinatology : official journal of the California Perinatal Association · 2023Article
- Effects of Total Enteral Nutrition on Early Growth, Immunity, and Neuronal Development of Preterm Infants.Nutrients · 2021Review
- Re: Zinc levels in neonatal life influence long-term neurodevelopment.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Quality improvement project designed to reduce disproportionate growth in extremely low gestational age neonates: cognitive neurodevelopmental outcome at 18-41 months.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Zinc levels in neonatal life influence long-term neurodevelopment.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Role of zinc in neonatal growth and brain growth: review and scoping review.Pediatric research · 2021Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the relationship of size for age with zinc deficiency in extremely low gestational age (GA) infants (23-28 weeks, ELGANs) who had insufficient linear growth despite optimizing other nutrients and to analyze changes in fronto-occipital circumference (FOC), weight and length with zinc supplementation. STUDY
designRetrospective cohort study.
resultsAmong 302 ELGANs, a serum zinc concentration was obtained in 52 with insufficient linear growth (17%). Zinc deficiency (serum concentration <0.74 mcg/ml) was diagnosed in 8 of 24 (33%) small for GA (SGA) compared to 35 of 278 (13%) non-SGA infants (P = 0.01). Zinc supplementation for >2 weeks improved FOC growth to discharge or 50 weeks postmenstrual age in infants with Zn deficiency. However, neither linear growth nor weight gain improved with Zn supplementation.
conclusionZinc deficiency was diagnosed in 14% ELGANs in this cohort. Zinc supplementation for >2 weeks improved FOC growth but not linear growth or weight gain.
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Registered trials
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