Evidence map›Paper›PMID 32788531›Full record

ArticleInternal medicine (Tokyo, Japan)2020

Therapeutic Plasma Exchange Improved Pregnancy-associated Thrombotic Microangiopathy but not the Pregnancy Outcome in Patient with Systemic Lupus Erythematosus.

Toshihiko Terasaki, Yuya Kondo, Mayumi Takahashi, Takashi Tawara, Akiko Fujita, Hiroya Yagi, Hitomi Kawai, Masayuki Noguchi, Ryota Sato, Mayu Terasaki and 8 more

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 1 institution in 1 country.

Toshihiko TerasakiDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan.
Yuya KondoDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan.
Mayumi TakahashiDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan.
Takashi TawaraDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan.
Akiko FujitaDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan.
Hiroya YagiDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Tsukuba, Japan.
Hitomi KawaiDepartment of Pathology, Institute of Basic Sciences, University of Tsukuba, Japan.
Masayuki NoguchiDepartment of Pathology, Institute of Basic Sciences, University of Tsukuba, Japan.
Ryota SatoDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan.
Mayu TerasakiDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan.
Shota OkamotoDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan.
Hirofumi TokoDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan.
Mizuki YagishitaDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan.
Hiroyuki TakahashiDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan.
Shinya HagiwaraDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan.
Hiroto TsuboiDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan.
Isao MatsumotoDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan.
Takayuki SumidaDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Japan.
University of Tsukuba · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombotic microangiopathy (TMA) is a rare but life-threatening complication of systemic lupus erythematosus (SLE) and is associated with adverse pregnancy outcomes. We herein report a 30-year-old pregnant woman with SLE complicated by TMA. Because her condition was unresponsive to initial corticosteroid and fresh-frozen plasma infusion treatment, we attempted plasma exchange (PE). Although thrombocytopenia and microangiopathic hemolytic anemia gradually improved, fetal death was confirmed at 23 weeks of gestation. This case suggests that PE is an effective therapeutic option but might be insufficient to maintain pregnancy in patients with SLE complicated by TMA.

Indexed as

Lupus Erythematosus, SystemicPurpura, Thrombotic ThrombocytopenicThrombotic MicroangiopathiesAdultFemaleHumansPlasma ExchangePregnancyPregnancy Outcomeplasma exchangepregnancysystemic lupus erythematosusthrombotic microangiopathy

Identifiers

PMID32788531
PMCPMC7807106
OpenAlexW3048419033

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.