Evidence map›Paper›PMID 32788388›Full record

ArticleJournal of neurointerventional surgery2021

eCLIPs bifurcation remodeling system for treatment of wide neck bifurcation aneurysms with extremely low dome-to-neck and aspect ratios: a multicenter experience.

Joost De Vries, Hieronymus D Boogaarts, Leif Sørensen, Markus Holtmannspoetter, Goetz Benndorf, Bernd Turowski, Georg Bohner, Shahram Derakhshani, Chema Navasa, Wim H van Zwam and 5 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Journal of neurointerventional surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. pCONUS 2 and pCONUS 2-HPC in the treatment of wide-necked intracranial aneurysms: Multicentre UK experience.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Contour-Assisted coiling with jailed microcatheter May result in better occlusion (CoCoJaMBO) in wide-necked intracranial aneurysms: Proof of principle and immediate angiographic results.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2023
    Article
  10. Review
  11. Article
  12. pCONUS 2 and pCONUS 2-HPC for the treatment of wide-necked intracranial aneurysms: Periprocedural, 6-month, and early 2-year follow-up outcomes.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2021
    Article
  13. Article
  14. Review
  15. Intrasaccular flow disruption (WEB) of a large wide-necked basilar apex aneurysm using PulseRider-assistance.Interdisciplinary neurosurgery : Advanced techniques and case management · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 13 institutions in 8 countries.

Joost De VriesNeurosurgery Department, Radboud University Medical Center, Nijmegen, The Netherlands.
Hieronymus D BoogaartsNeurosurgery Department, Radboud University Medical Center, Nijmegen, The Netherlands.
Leif SørensenNeuroradiology, Aarhus University Hospital, Aarhus, Denmark.
Markus HoltmannspoetterDiagnostic and Interventional Neuroradiology, Rigshospitalet, Kobenhavn, Denmark.
Goetz BenndorfINR, Rigshospital Copenhagen, Copenhagen, Denmark.
Bernd TurowskiRadiology, University of Duesseldorf, Düsseldorf, Germany.
Georg BohnerNeuroradiology, Charite Universitatsmedizin Berlin, Berlin, Germany.
Shahram DerakhshaniNeuroradiology, Essex Center for Neurological Sciences, Queen's University Hospital, Romdord, UK.
Chema NavasaNeuroradiology, Hospital Universitario Miguel Servet, Zaragoza, Spain.
Wim H van ZwamRadiology, Maastricht University Medical Center, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0003-1631-7056
Michael SödermanDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Riitta RautioDepartment of Radiology, TYKS, Turku, Finland.ORCID http://orcid.org/0000-0001-8385-0622
Christian MathysInstitute of Radiology and Neuroradiology, Evangelisches Krankenhaus, University of Oldenburg, Oldenburg, Germany.
Howard RiinaNeurosurgery, NYU, New York, New York, USA.
Thomas R MarottaDiagnostic and Therapeutic Neuroradiology, St Michael's Hospital, Toronto, Ontario, Canada Tom.Marotta@Unityhealth.to.ORCID http://orcid.org/0000-0002-2480-2054
Radboud University Nijmegen · NLAarhus University Hospital · DKBaylor College of Medicine · USCarl von Ossietzky Universität Oldenburg · DECharité - Universitätsmedizin Berlin · DEHeinrich Heine University Düsseldorf · DEHospital Universitario Miguel Servet · ESKarolinska University Hospital · SEMaastricht University · NLNew York University · USQueen's Hospital · GBRigshospitalet · DKSt. Michael's Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWide necked bifurcation aneurysms (WNBA) are among the most difficult aneurysms to treat. Very low dome-to-neck (DTN) and aspect ratios provide an even greater challenge in the management of WNBAs. We present the safety and efficacy profile for endovascular clip system (eCLIPs) device in the treatment of this subset of WNBAs with very unfavorable morphologies.

methodsIn our case series, 24 patients treated at 12 international centers were taken from a larger prospective voluntary post-marketing registry of 65 patients treated with the eCLIPs device and coiling. Those who had WNBAs at either the carotid or basilar terminus with a DTN ratio <1.6 and aspect ratio <1.2 were included. Radiologic and clinical outcomes were assessed immediately after the procedure and at the latest follow-up.

resultsThe eCLIPs device was successfully deployed in 23 cases (96%). One patient (4.2%) died due to guidewire perforation distal to the implant site. No other complications were documented. After a mean follow-up of 15.8 months (range 3-40 months), good radiologic outcomes (modified Raymond-Roy classification (MRRC) scores of 1 or 2) were documented in 20 of 21 patients (95%) with follow-up data. The lone patient with an MRRC score of 3 showed coiled compaction after incomplete neck coverage with the device.

conclusionOur series of patients with aneurysms having adverse DTN and aspect ratios demonstrated that the eCLIPs device has a safety and efficacy profile comparable with currently available devices in the treatment of WNBAs.

Indexed as

Surgical InstrumentsAdultAgedCohort StudiesEndovascular ProceduresFemaleFollow-Up StudiesHumansIntracranial AneurysmMaleMiddle AgedProspective StudiesRegistriesTreatment Outcomeaneurysmdevice

Identifiers

PMID32788388
PMCPMC8053345
OpenAlexW3048468813

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.