Evidence map›Paper›PMID 32788378›Full record

ArticlemBio2020

Visualizing Nudivirus Assembly and Egress.

Sailakshmi Velamoor, Allan Mitchell, Bruno M Humbel, WonMo Kim, Charlotte Pushparajan, Gabriel Visnovsky, Laura N Burga, Mihnea Bostina

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Functional characterization ofJournal of virology · 2023
    Article
  4. Article
  5. A filamentous archaeal virus is enveloped inside the cell and released through pyramidal portals.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Sailakshmi VelamoorDepartment of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.
Allan MitchellOtago Micro and Nano Imaging, Electron Microscopy, University of Otago, Dunedin, New Zealand.
Bruno M HumbelIMG, Okinawa Institute of Science and Technology, Okinawa, Japan.
WonMo KimDepartment of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.
Charlotte PushparajanDepartment of Chemical and Process Engineering Department, University of Canterbury, Christchurch, New Zealand.
Gabriel VisnovskyDepartment of Chemical and Process Engineering Department, University of Canterbury, Christchurch, New Zealand.
Laura N BurgaDepartment of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.
Mihnea BostinaDepartment of Microbiology and Immunology, University of Otago, Dunedin, New Zealand mihnea.bostina@otago.ac.nz.ORCID 0000-0003-3621-3772
University of Otago · NZUniversity of Canterbury · NZOkinawa Institute of Science and Technology Graduate University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enveloped viruses hijack cellular membranes in order to provide the necessary material for virion assembly. In particular, viruses that replicate and assemble inside the nucleus have developed special approaches to modify the nuclear landscape for their advantage. We used electron microscopy to investigate cellular changes occurring during nudivirus infection and we characterized a unique mechanism for assembly, packaging, and transport of new virions across the nuclear membrane and through the cytoplasm. Our three-dimensional reconstructions describe the complex remodeling of the nuclear membrane necessary to release vesicle-associated viruses into the cytoplasm. This is the first report of nuclear morphological reconfigurations that occur during nudiviral infection.

Indexed as

Virus AssemblyVirus ReleaseAnimalsCell LineCell NucleusCryoelectron MicroscopyInsectaNuclear EnvelopeNudiviridaeelectron microscopyenveloped virusesnudivirusesviral assembly

Identifiers

PMID32788378
PMCPMC7439470
OpenAlexW3048442370

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.