Evidence map›Paper›PMID 32788298›Full record

ArticleeNeuro

Kainate Receptor Auxiliary Subunit NETO2-Related Cued Fear Conditioning Impairments Associate with Defects in Amygdala Development and Excitability.

Marie Mennesson, Ester Orav, Adrien Gigliotta, Natalia Kulesskaya, Suvi Saarnio, Anna Kirjavainen, Sebnem Kesaf, Frederike Winkel, Maria Llach Pou, Juzoh Umemori and 6 more

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Kainate Receptor Antagonists: Recent Advances and Therapeutic Perspective.International journal of molecular sciences · 2023
    Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 4 countries.

Marie MennessonDepartment of Psychology and Logopedics, Medicum, University of Helsinki, Helsinki 00290, Finland.
Ester OravMolecular and Integrative Biosciences Research Program, University of Helsinki, Helsinki 00790, Finland.
Adrien GigliottaDepartment of Psychology and Logopedics, Medicum, University of Helsinki, Helsinki 00290, Finland.
Natalia KulesskayaMolecular and Integrative Biosciences Research Program, University of Helsinki, Helsinki 00790, Finland.
Suvi SaarnioMolecular and Integrative Biosciences Research Program, University of Helsinki, Helsinki 00790, Finland.
Anna KirjavainenMolecular and Integrative Biosciences Research Program, University of Helsinki, Helsinki 00790, Finland.
Sebnem KesafMolecular and Integrative Biosciences Research Program, University of Helsinki, Helsinki 00790, Finland.ORCID 0000-0002-6611-6159
Frederike WinkelNeuroscience Center, Helsinki Institute of Life Science HiLIFE, University of Helsinki, Helsinki 00290, Finland.
Maria Llach PouNeuroscience Center, Helsinki Institute of Life Science HiLIFE, University of Helsinki, Helsinki 00290, Finland.
Juzoh UmemoriNeuroscience Center, Helsinki Institute of Life Science HiLIFE, University of Helsinki, Helsinki 00290, Finland.
Vootele VoikarNeuroscience Center, Helsinki Institute of Life Science HiLIFE, University of Helsinki, Helsinki 00290, Finland.ORCID 0000-0003-4201-8666
Victoria RisbroughCenter of Excellence for Stress and Mental Health, Veterans Affairs, La Jolla, CA 92093.
Juha PartanenMolecular and Integrative Biosciences Research Program, University of Helsinki, Helsinki 00790, Finland.
Eero CastrénNeuroscience Center, Helsinki Institute of Life Science HiLIFE, University of Helsinki, Helsinki 00290, Finland.
Sari E LauriMolecular and Integrative Biosciences Research Program, University of Helsinki, Helsinki 00790, Finland iiris.hovatta@helsinki.fi sari.lauri@helsinki.fi.ORCID 0000-0002-5895-1357
Iiris HovattaDepartment of Psychology and Logopedics, Medicum, University of Helsinki, Helsinki 00290, Finland iiris.hovatta@helsinki.fi sari.lauri@helsinki.fi.ORCID 0000-0002-5990-7892
University of Helsinki · FIUniversity of California System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NETO2 is an auxiliary subunit for kainate-type glutamate receptors that mediate normal cued fear expression and extinction. Since the amygdala is critical for these functions, we asked whether

Indexed as

FearKainic Acid ReceptorsAmygdalaAnimalsInterneuronsMembrane ProteinsMiceParvalbuminsKainic Acid ReceptorsMembrane ProteinsNETO2 protein, mouseParvalbuminsamygdalaexcitabilityfear conditioningimmunohistochemistryinterneuronknock-out mouse

Identifiers

PMID32788298
PMCPMC7470932
OpenAlexW3048588897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.