Evidence map›Paper›PMID 32788280›Full record

Trial reportDiabetes care2020

An Observational Study of the Equivalence of Age and Duration of Diabetes to Glycemic Control Relative to the Risk of Complications in the Combined Cohorts of the DCCT/EDIC Study.

Ionut Bebu, Barbara H Braffett, David Schade, William Sivitz, John I Malone, Rodica Pop-Busui, Gayle M Lorenzi, Pearl Lee, Victoria R Trapani, Amisha Wallia and 3 more

Open access · bronzeAbstract readMulticenter StudyObservational StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Diabetes care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Ionut BebuBiostatistics Center, The George Washington University, Rockville, MD ibebu@bsc.gwu.edu.ORCID 0000-0002-4944-7968
Barbara H BraffettBiostatistics Center, The George Washington University, Rockville, MD.ORCID 0000-0002-2184-9754
David SchadeThe University of New Mexico, Albuquerque, NM.ORCID 0000-0003-1921-604X
William SivitzThe University of Iowa, Iowa City, IA.ORCID 0000-0002-7829-0189
John I MaloneUniversity of South Florida, Tampa, FL.
Rodica Pop-BusuiUniversity of Michigan, Ann Arbor, MI.ORCID 0000-0002-2042-1350
Gayle M LorenziUniversity of California, San Diego, La Jolla, CA.
Pearl LeeUniversity of Michigan, Ann Arbor, MI.ORCID 0000-0002-4678-4168
Victoria R TrapaniBiostatistics Center, The George Washington University, Rockville, MD.
Amisha WalliaNorthwestern University, Evanston, IL.ORCID 0000-0002-3183-4062
William H HermanUniversity of Michigan, Ann Arbor, MI.ORCID 0000-0002-0502-674X
John M LachinORCID 0000-0001-9838-2841
DCCT/EDIC Research Group
George Washington University · USUniversity of Michigan · USNorthwestern University · USUniversity of California San Diego · USUniversity of Iowa · USUniversity of New Mexico · USUniversity of South Florida · US

Funding

Limited Competition for the Continuation of Epidemiology of Diabetes Interventions and Complications (EDIC) Study Clinical Research Center (Collaborative U01)U01DK094157 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI Ionut Bebu, Barbara Halina Braffett · 2011 to 2026
$97.6M
Epidemiology of Diabetes Interventions and Complications Data Coordinating CenterU01DK094176 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI BEBU, IONUT, BRAFFETT, BARBARA HALINA · 2012 to 2022
$30.8M
Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
NIDDK NIH HHS P30 DK020572NIDDK NIH HHS P30 DK092926NIDDK NIH HHS U01 DK094157NIDDK NIH HHS U01 DK094176
6 · The paper itself

Abstract

objectiveThis epidemiological analysis of the pooled Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) cohort describes the equivalence of a 1-percentage point increase in HbA RESEARCH DESIGN AND

methodsSeparate Cox proportional hazards models determined the number of additional years of age and/or duration of T1D that would result in the same increase in risk of microvascular (retinopathy, nephropathy, and neuropathy) and cardiovascular complications and mortality as a 1-percentage point increase in HbA

resultsThe risk of any cardiovascular disease associated with a 1-percentage point increase in HbA

conclusionsOur results help evaluate the impact of glycemia on advanced complications in a way that may be more interpretable to health care providers and individuals with T1D.

Indexed as

Glycemic ControlAdolescentAdultAge FactorsAge of OnsetBlood GlucoseChildChild, PreschoolCohort StudiesDiabetes ComplicationsDiabetes Mellitus, Type 1FemaleGlycated HemoglobinHumansMaleMiddle AgedBlood GlucoseGlycated Hemoglobin

Identifiers

PMID32788280
PMCPMC7510046
OpenAlexW3048466595

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.