Evidence map›Paper›PMID 32788210›Full record

ArticleThe Journal of biological chemistry2020

Potassium starvation induces autophagy in yeast.

Nambirajan Rangarajan, Ishani Kapoor, Shuang Li, Peter Drossopoulos, Kristen K White, Victoria J Madden, Henrik G Dohlman

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. The engagement of autophagy in maniac disease.CNS neuroscience & therapeutics · 2023
    Review
  7. Article
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nambirajan RangarajanDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0002-8332-2448
Ishani KapoorDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Shuang LiDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0003-4658-9765
Peter DrossopoulosDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Kristen K WhiteMicroscopy Services Laboratory, Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Victoria J MaddenMicroscopy Services Laboratory, Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID 0000-0002-7909-7743
Henrik G DohlmanDepartment of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA henrik_dohlman@med.unc.edu.
University of North Carolina at Chapel Hill · US

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Deborah F. Tate · 1985 to 2026
$201.5M
Negative and positive feedback in cell signalingR35GM118105 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Henrik G. Dohlman · 2016 to 2026
$6.6M
NCI NIH HHS P30 CA016086NIGMS NIH HHS R35 GM118105
6 · The paper itself

Abstract

Autophagy is a conserved process that recycles cellular contents to promote survival. Although nitrogen limitation is the canonical inducer of autophagy, recent studies have revealed several other nutrients important to this process. In this study, we used a quantitative, high-throughput assay to identify potassium starvation as a new and potent inducer of autophagy in the yeast

Indexed as

AutophagyAutophagy-Related Protein 5Autophagy-Related ProteinsClass III Phosphatidylinositol 3-KinasesPhosphatidylinositol 3-KinasesPotassiumProtein KinasesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsATG1 protein, S cerevisiaeATG5 protein, S cerevisiaeAutophagy-Related Protein 5Autophagy-Related ProteinsClass III Phosphatidylinositol 3-KinasesPhosphatidylinositol 3-KinasesPotassiumProtein KinasesSaccharomyces cerevisiae Proteinsautophagyelectron microscopyphosphatidylinositide 3-kinase (PI 3-kinase)potassiumRNA sequencingstarvationtranscriptomicsyeast

Identifiers

PMID32788210
PMCPMC7549029
OpenAlexW3048939674

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.