Evidence map›Paper›PMID 32788085›Full record

ReviewBiological psychiatry. Cognitive neuroscience and neuroimaging2021

Neuroimaging Markers of Resiliency in Youth at Clinical High Risk for Psychosis: A Qualitative Review.

Teresa Vargas, Katherine S F Damme, Arielle Ered, Riley Capizzi, Isabelle Frosch, Lauren M Ellman, Vijay A Mittal

Open access · greenAbstract readReview
In one paragraph

Review in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Risk and Resilience in Extraordinary Times.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2021
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Teresa VargasDepartment of Psychology, Northwestern University, Evanston, Illinois. Electronic address: teresavargas@u.northwestern.edu.
Katherine S F DammeDepartment of Psychology, Northwestern University, Evanston, Illinois.
Arielle EredDepartment of Psychology, Temple University, Philadelphia, Pennsylvania.
Riley CapizziDepartment of Psychology, Temple University, Philadelphia, Pennsylvania.
Isabelle FroschDepartment of Psychology, Northwestern University, Evanston, Illinois.
Lauren M EllmanDepartment of Psychology, Temple University, Philadelphia, Pennsylvania.
Vijay A MittalDepartment of Psychology, Northwestern University, Evanston, Illinois; Department of Psychiatry, Northwestern University, Evanston, Illinois; Department of Medical Social Sciences, Northwestern University, Evanston, Illinois; Institute for Policy Research, Northwestern University, Evanston, Illinois; Institute for Innovations in Developmental Sciences, Northwestern University, Evanston, Illinois.
Northwestern University · USTemple University · US

Funding

Maternal Inflammation During Pregnancy: Clinical and Neurocognitive Outcomes in Adult OffspringR01MH118545 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ELLMAN, LAUREN M · 2019 to 2023
$3.3M
Prodromal Inventory for Negative Symptoms (PINS): A Development and Validation StudyR01MH116039 · NIMH · UNIVERSITY OF GEORGIA · PI MITTAL, VIJAY A, STRAUSS, GREGORY P · 2019 to 2023
$3.1M
2/5 CAPER Computerized assessment of psychosis riskR01MH120088 · NIMH · NORTHWESTERN UNIVERSITY · PI MITTAL, VIJAY A · 2020 to 2024
$2.0M
1/3-Community Psychosis Risk Screening: An Instrument Development Study SupplementR01MH112613 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ELLMAN, LAUREN M · 2017 to 2022
$1.8M
CAPER: Computerized Assessment of Psychosis Risk SupplementR01MH120091 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ELLMAN, LAUREN M · 2020 to 2024
$1.6M
2/3 Community psychosis risk screening: An instrument development studyR01MH112545 · NIMH · NORTHWESTERN UNIVERSITY · PI MITTAL, VIJAY A · 2017 to 2021
$1.2M
Neural Habituation in Ultra High-Risk YouthR21MH110374 · NIMH · NORTHWESTERN UNIVERSITY · PI MITTAL, VIJAY A · 2017 to 2018
$445k
Using Speech Acoustics to Reveal Motor Disruptions in PsychosisR21MH119677 · NIMH · NORTHWESTERN UNIVERSITY · PI GOLDRICK, MATTHEW A, MITTAL, VIJAY A · 2019 to 2020
$424k
Cumulative environmental risk exposure in youth at clinical high-risk for psychosisF31MH119776 · NIMH · NORTHWESTERN UNIVERSITY · PI VARGAS, TERESA · 2019 to 2021
$120k
The Impact of Stress and Trauma on White Matter Integrity and Psychotic-like ExperiencesF31MH119720 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ERED, ARIELLE · 2019 to 2021
$52k
NIMH NIH HHS F31 MH119720NIMH NIH HHS F31 MH119776NIMH NIH HHS R01 MH112545NIMH NIH HHS R01 MH112613NIMH NIH HHS R01 MH116039NIMH NIH HHS R01 MH118545NIMH NIH HHS R01 MH120088NIMH NIH HHS R01 MH120091NIMH NIH HHS R21 MH110374NIMH NIH HHS R21 MH119677
6 · The paper itself

Abstract

Psychotic disorders are highly debilitating and constitute a major public health burden. Identifying markers of psychosis risk and resilience is a necessary step toward understanding etiology and informing prevention and treatment efforts in individuals at clinical high risk (CHR) for psychosis. In this context, it is important to consider that neural risk markers have been particularly useful in identifying mechanistic determinants along with predicting clinical outcomes. Notably, despite a growing body of supportive literature and the promise of recent findings identifying potential neural markers, the current work on CHR resilience markers has received little attention. The present review provides a brief overview of brain-based risk markers with a focus on predicting symptom course. Next, the review turns to protective markers, examining research from nonpsychiatric and schizophrenia fields to build an understanding of framing, priorities, and potential, applying these ideas to contextualizing a small but informative body of resiliency-relevant CHR research. Four domains (neurocognition, emotion regulation, allostatic load, and sensory and sensorimotor function) were identified and are discussed in terms of behavioral and neural markers. Taken together, the literature suggests significant predictive value for brain-based markers for individuals at CHR for psychosis, and the limited but compelling resiliency work highlights the critical importance of expanding this promising area of inquiry.

Indexed as

Psychotic DisordersSchizophreniaAdolescentBiomarkersBrainHumansNeuroimagingBiomarkersBiomarkerClinical high risk for psychosisMagnetic resonance imagingNeuroimagingResilienceSchizophrenia

Identifiers

PMID32788085
PMCPMC7725930
OpenAlexW3034993845

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.