Evidence map›Paper›PMID 32787941›Full record

ArticleRadiation oncology (London, England)2020

Low-dose cone-beam CT (LD-CBCT) reconstruction for image-guided radiation therapy (IGRT) by three-dimensional dual-dictionary learning.

Ying Song, Weikang Zhang, Hong Zhang, Qiang Wang, Qing Xiao, Zhibing Li, Xing Wei, Jialu Lai, Xuetao Wang, Wan Li and 4 more

Open access · goldAbstract read
In one paragraph

Article in Radiation oncology (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Low-dose CBCT image reconstruction: a review.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Ying SongDepartment of Radiotherapy, Cancer Center, West China Hospital, Sichuan University, No.37 Guo Xue Alley, Chengdu, 610065, P. R. China.
Weikang ZhangThe School of Biomedical Engineering, Shanghai Jiao Tong University, No. 800, Dongchuan Road, Minhang District, Shanghai, 610065, P. R. China.
Hong ZhangDepartment of Radiotherapy, Cancer Center, West China Hospital, Sichuan University, No.37 Guo Xue Alley, Chengdu, 610065, P. R. China.
Qiang WangDepartment of Radiotherapy, Cancer Center, West China Hospital, Sichuan University, No.37 Guo Xue Alley, Chengdu, 610065, P. R. China.
Qing XiaoDepartment of Radiotherapy, Cancer Center, West China Hospital, Sichuan University, No.37 Guo Xue Alley, Chengdu, 610065, P. R. China.
Zhibing LiDepartment of Radiotherapy, Cancer Center, West China Hospital, Sichuan University, No.37 Guo Xue Alley, Chengdu, 610065, P. R. China.
Xing WeiDepartment of Radiotherapy, Cancer Center, West China Hospital, Sichuan University, No.37 Guo Xue Alley, Chengdu, 610065, P. R. China.
Jialu LaiDepartment of Radiotherapy, Cancer Center, West China Hospital, Sichuan University, No.37 Guo Xue Alley, Chengdu, 610065, P. R. China.
Xuetao WangDepartment of Radiotherapy, Cancer Center, West China Hospital, Sichuan University, No.37 Guo Xue Alley, Chengdu, 610065, P. R. China.
Wan LiDepartment of Radiotherapy, Cancer Center, West China Hospital, Sichuan University, No.37 Guo Xue Alley, Chengdu, 610065, P. R. China.
Quan ZhongDepartment of Radiotherapy, Cancer Center, West China Hospital, Sichuan University, No.37 Guo Xue Alley, Chengdu, 610065, P. R. China.
Pan GongDepartment of Radiotherapy, Cancer Center, West China Hospital, Sichuan University, No.37 Guo Xue Alley, Chengdu, 610065, P. R. China.
Renming ZhongDepartment of Radiotherapy, Cancer Center, West China Hospital, Sichuan University, No.37 Guo Xue Alley, Chengdu, 610065, P. R. China. zrm_100@163.com.
Jun ZhaoThe School of Biomedical Engineering, Shanghai Jiao Tong University, No. 800, Dongchuan Road, Minhang District, Shanghai, 610065, P. R. China. junzhao@sjtu.edu.cn.
Sichuan University · CNShanghai Jiao Tong University · CN

Funding

National Natural Science Foundation of China 81803056
6 · The paper itself

Abstract

backgroundTo develop a low-dose cone beam CT (LD-CBCT) reconstruction method named simultaneous algebraic reconstruction technique and dual-dictionary learning (SART-DDL) joint algorithm for image guided radiation therapy (IGRT) and evaluate its imaging quality and clinical application ability.

methodsIn this retrospective study, 62 CBCT image sets from February 2018 to July 2018 at west china hospital were randomly collected from 42 head and neck patients (mean [standard deviation] age, 49.7 [11.4] years, 12 females and 30 males). All image sets were retrospectively reconstructed by SART-DDL (resultant D-CBCT image sets) with 18% less clinical raw projections. Reconstruction quality was evaluated by quantitative parameters compared with SART and Total Variation minimization (SART-TV) joint reconstruction algorithm with paired t test. Five-grade subjective grading evaluations were done by two oncologists in a blind manner compared with clinically used Feldkamp-Davis-Kress algorithm CBCT images (resultant F-CBCT image sets) and the grading results were compared by paired Wilcoxon rank test. Registration results between D-CBCT and F-CBCT were compared. D-CBCT image geometry fidelity was tested.

resultsThe mean peak signal to noise ratio of D-CBCT was 1.7 dB higher than SART-TV reconstructions (P < .001, SART-DDL vs SART-TV, 36.36 ± 0.55 dB vs 34.68 ± 0.28 dB). All D-CBCT images were recognized as clinically acceptable without significant difference with F-CBCT in subjective grading (P > .05). In clinical registration, the maximum translational and rotational difference was 1.8 mm and 1.7 degree respectively. The horizontal, vertical and sagittal geometry fidelity of D-CBCT were acceptable.

conclusionsThe image quality, geometry fidelity and clinical application ability of D-CBCT are comparable to that of the F-CBCT for head-and-neck patients with 18% less projections by SART-DDL.

Indexed as

Cone-Beam Computed TomographyFemaleHead and Neck NeoplasmsHumansImage Processing, Computer-AssistedImaging, Three-DimensionalMaleMiddle AgedOrgans at RiskPrognosisRadiotherapy DosageRadiotherapy, Image-GuidedRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedRetrospective StudiesSquamous Cell Carcinoma of Head and NeckCBCT reconstructionDictionary learningLow doseRadiation therapy

Identifiers

PMID32787941
PMCPMC7425566
OpenAlexW3048892410

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.