Evidence map›Paper›PMID 32787935›Full record

ArticleParasites & vectors2020

Clinical helminthiases in Thailand border regions show elevated prevalence levels using qPCR diagnostics combined with traditional microscopic methods.

Poom Adisakwattana, Tippayarat Yoonuan, Orawan Phuphisut, Akkarin Poodeepiyasawat, Nirundorn Homsuwan, Catherine A Gordon, Donald P McManus, Louise E Atkinson, Angela Mousley, Geoffrey N Gobert

Open access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Poom AdisakwattanaDepartment of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand. poom.adi@mahidol.edu.
Tippayarat YoonuanDepartment of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.
Orawan PhuphisutDepartment of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.
Akkarin PoodeepiyasawatDepartment of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.
Nirundorn HomsuwanDepartment of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.
Catherine A GordonMolecular Parasitology Laboratory, Infectious Diseases Division, QIMR Berghofer Medical Research Institute, Brisbane, 4006, Australia.
Donald P McManusMolecular Parasitology Laboratory, Infectious Diseases Division, QIMR Berghofer Medical Research Institute, Brisbane, 4006, Australia.
Louise E AtkinsonSchool of Biological Sciences, Queen's University Belfast, Belfast, BT9 5DL, UK.
Angela MousleySchool of Biological Sciences, Queen's University Belfast, Belfast, BT9 5DL, UK.
Geoffrey N GobertSchool of Biological Sciences, Queen's University Belfast, Belfast, BT9 5DL, UK. g.gobert@qub.ac.uk.ORCID http://orcid.org/0000-0001-5884-6453
Mahidol University · THQueen's University Belfast · GBQIMR Berghofer Medical Research Institute · AU

Funding

Biotechnology and Biological Sciences Research Council BB/H019472/1National Health and Medical Research Council APP1037304National Health and Medical Research Council APP1098244National Health and Medical Research Council ID613671Northern Ireland Department of Economy DFEGCRF17-18/Gobert
6 · The paper itself

Abstract

backgroundUnder-regulated national borders in Southeast Asia represent potential regions for enhanced parasitic helminth transmission and present barriers to helminthiasis disease control.

methodsThree Thailand border regions close to Myanmar, Laos and Cambodia were surveyed for clinical parasitic helminth disease. In-field microscopy was performed on stools from 567 individuals. Sub-samples were transported to Bangkok for molecular analysis comprising three multiplex qPCR assays.

resultsThe overall helminth infection prevalence was 17.99% as assessed by Kato-Katz and 24.51% by qPCR. The combined prevalence of the two methods was 28.57%; the most predominant species detected were Opisthorchis viverrini (18.34%), hookworm (6.88%; Ancylostoma spp. and Necator americanus), Ascaris lumbricoides (2.29%) and Trichuris trichiura (1.76%).

conclusionsThese data demonstrate the value of molecular diagnostics for determining more precise prevalence levels of helminthiases in Southeast Asia. Availability of such accurate prevalence information will help guide future public health initiatives and highlights the need for more rigorous surveillance and timely intervention in these regions.

Indexed as

PrevalenceAncylostomaAncylostomatoideaAnimalsAscaris lumbricoidesAsia, SoutheasternFecesFemaleHelminthiasisHelminthsHumansMaleNecator americanusOpisthorchisPathology, MolecularReal-Time Polymerase Chain ReactionHelminthiasesKato-Katzmolecular diagnosticsqPCRSoutheast AsiaThailand border regions

Identifiers

PMID32787935
PMCPMC7425172
OpenAlexW3048476341

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.