Evidence map›Paper›PMID 32787926›Full record

ReviewEuropean journal of medical research2020

Face masks: benefits and risks during the COVID-19 crisis.

Christiane Matuschek, Friedrich Moll, Heiner Fangerau, Johannes C Fischer, Kurt Zänker, Martijn van Griensven, Marion Schneider, Detlef Kindgen-Milles, Wolfram Trudo Knoefel, Artur Lichtenberg and 16 more

Open access · goldAbstract readReview
In one paragraph

Review in European journal of medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 1 pooled it
25.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 1 synthesis or guideline pooled it, 249 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  5. Review
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  7. Article
  8. Assessing the behavior of food handlers wearing face masks and the passage of bacteria through disposable masks.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  9. Article
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  16. Facial expression and emotion.Laryngo- rhino- otologie · 2023
    Article
  17. The effect of N95 respirators on vital parameters, PETCOIrish journal of medical science · 2023
    Article
  18. Article
  19. Article
  20. Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 8 institutions in 3 countries.

Christiane MatuschekDepartment of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany.
Friedrich MollDepartment of the History, Philosophy and Ethics of Medicine, Heinrich Heine University, Medical Faculty, Dusseldorf, Germany.
Heiner FangerauDepartment of the History, Philosophy and Ethics of Medicine, Heinrich Heine University, Medical Faculty, Dusseldorf, Germany.
Johannes C FischerInstitute for Transplant Diagnostics and Cell Therapeutics, Heinrich Heine University, Dusseldorf, Germany.
Kurt ZänkerCenter for Biomedical Education and Research (ZBAF), University Witten/Herdecke, Witten, Germany.
Martijn van GriensvenDepartment cBITE, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, Maastricht, The Netherlands.ORCID https://orcid.org/0000-0001-5104-9881
Marion SchneiderDepartment of Experimental Anesthesiology, University of Ulm, Ulm, Germany.
Detlef Kindgen-MillesDepartment of Anesthesiology and Intensive Care Medicine, Heinrich Heine University, Dusseldorf, Germany.
Wolfram Trudo KnoefelDepartment for General Visceral and Pediatric Surgery, Heinrich Heine University, Dusseldorf, Germany.
Artur LichtenbergDepartment for Cardiac Surgery, Heinrich Heine University, Dusseldorf, Germany.
Balint TamaskovicsDepartment of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany.
Freddy Joel Djiepmo-NjanangDepartment of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany.
Wilfried BudachDepartment of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany.
Stefanie CorradiniDepartment of Radiation Oncology, University Hospital, LMU Munich, Germany.
Dieter HäussingerDepartment of Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University, Dusseldorf, Germany.
Torsten FeldtDepartment of Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University, Dusseldorf, Germany.
Björn JensenDepartment of Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University, Dusseldorf, Germany.
Rainer PelkaInstitute for Applied Statistics, Munich, Germany.
Klaus OrthUniversity of Hannover, Hannover, Germany.
Matthias PeiperHeinrich-Heine-University, Dusseldorf, Germany.
Olaf GrebeDepartment for Cardiology, Rhythmology and Intensive Care Medicine, Evangelic Hospital, Dusseldorf, Germany.
Kitti MaasDepartment of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany.
Peter Arne GerberHeinrich-Heine-University, Dusseldorf, Germany.
Alessia PedotoDepartment of Anesthesiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Edwin BölkeDepartment of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany. boelke@med.uni-duesseldorf.de.ORCID http://orcid.org/0000-0001-9112-1024
Jan HaussmannDepartment of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany.
Heinrich Heine University Düsseldorf · DEEvangelisches Krankenhaus Düsseldorf · DEInstitut für Angewandte Statistik · DELMU Klinikum · DEMaastricht University · NLMemorial Sloan Kettering Cancer Center · USUniversität Ulm · DEWitten/Herdecke University · DE

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Elisa de Stanchina · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundThe German government has made it mandatory to wear respiratory masks covering mouth and nose (MNC) as an effective strategy to fight SARS-CoV-2 infections. In many countries, this directive has been extended on shopping malls or public transportation. The aim of this paper is to critically analyze the statutory regulation to wear protective masks during the COVID-19 crisis from a medical standpoint.

methodsWe performed an extensive query of the most recent publications addressing the prevention of viral infections including the use of face masks in the community as a method to prevent the spread of the infection. We addressed the issues of practicability, professional use, and acceptability based on the community and the environment where the user resided.

resultsUpon our critical review of the available literature, we found only weak evidence for wearing a face mask as an efficient hygienic tool to prevent the spread of a viral infection. However, the use of MNC seems to be linked to relevant protection during close contact scenarios by limiting pathogen-containing aerosol and liquid droplet dissemination. Importantly, we found evidence for significant respiratory compromise in patients with severe obstructive pulmonary disease, secondary to the development of hypercapnia. This could also happen in patients with lung infections, with or without SARS-CoV-2.

conclusionEpidemiologists currently emphasize that wearing MNC will effectively interrupt airborne infections in the community. The government and the politicians have followed these recommendations and used them to both advise and, in some cases, mandate the general population to wear MNC in public locations. Overall, the results seem to suggest that there are some clinically relevant scenarios where the use of MNC necessitates more defined recommendations. Our critical evaluation of the literature both highlights the protective effects of certain types of face masks in defined risk groups, and emphasizes their potential risks.

Indexed as

Practice Guidelines as TopicCoronavirus InfectionsCOVID-19Equipment and Supplies UtilizationHumansMasksPandemicsPneumonia, ViralPre-Exposure ProphylaxisRespiratory Protective Devices

Identifiers

PMID32787926
PMCPMC7422455
OpenAlexW3048499255

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.