Evidence map›Paper›PMID 32787794›Full record

ArticleBMC neurology2020

Central nervous system Cryptococcoma mimicking demyelinating disease: a case report.

Jie Wei, Xiang-Yu Li, Yue Zhang

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Cryptococcus neoformans, a global threat to human health.Infectious diseases of poverty · 2023
    Review
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jie WeiDepartment of neurology, 905th hospital of PLA Navy, No 1328 Huashan Road, Changning District, Shanghai, 200052, China.
Xiang-Yu LiDepartment of Laboratory Medicine, Huashan Hospital North, Fudan University, No 108 Luxiang Road, Baoshan District, Shanghai, 201907, China.
Yue ZhangDepartment of Neurology, Huashan Hospital, Fudan University, No.12 Wulumuqi Road, Jing'an District, Shanghai, 200040, China. zygadene@163.com.ORCID http://orcid.org/0000-0002-1572-7910
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCerebral cryptococcomas is a rare form of central nervous system cryptococcosis. Most previous cases were mistaken for neoplasm before surgery. We present a case of cerebral cryptococcomas whose radiological profiles resembled demyelinating disease, especially tumefactive demyelinating lesion. CASE PRESENTATION: A 40-year-old male was admitted for 1-week-long unconsciousness. Brain MRI revealed a rim-enhanced mass within the corpus callosum body. Central nervous system demyelinating disease was suspected. Empirical corticosteroid treatment led to some improvement, but his condition deteriorated 2 months later. Brain MRI revealed punctate new foci. Cryptococcus neoformans was detected in cerebrospinal fluid. Cryptococcus antigen test was positive in his current and previous cerebrospinal fluid samples. The patient died despite standard antifungal treatment.

conclusionDiagnosis of cerebral cryptococcomas is challenging. It may mimic demyelinating diseases.

Indexed as

AdultAntigens, FungalCentral Nervous System Bacterial InfectionsCryptococcosisCryptococcus neoformansDemyelinating DiseasesDiagnosis, DifferentialHumansMagnetic Resonance ImagingMaleNeuroimagingAntigens, FungalCentral nervous system cryptococcosisCorticosteroidCryptococcomasTumefactive demyelinating lesion

Identifiers

PMID32787794
PMCPMC7422497
OpenAlexW3048678978

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.