Evidence map›Paper›PMID 32787464›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2020

Alternative splicing of leptin receptor overlapping transcript in osteosarcoma.

Emel Rothzerg, Xuan D Ho, Jiake Xu, David Wood, Aare Märtson, Katre Maasalu, Sulev Kõks

Open access · greenAbstract read
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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  7. Innovative approaches for treatment of osteosarcoma.Experimental biology and medicine (Maywood, N.J.) · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Emel RothzergSchool of Biomedical Sciences, The University of Western Australia, Perth, WA 6009, Australia.ORCID 0000-0003-1957-930X
Xuan D HoDepartment of Oncology, College of Medicine and Pharmacy, Hue University, Hue 53000, Vietnam.
Jiake XuSchool of Biomedical Sciences, The University of Western Australia, Perth, WA 6009, Australia.
David WoodSchool of Biomedical Sciences, The University of Western Australia, Perth, WA 6009, Australia.
Aare MärtsonDepartment of Traumatology and Orthopaedics, University of Tartu, Tartu University Hospital, Tartu 50411, Estonia.
Katre MaasaluDepartment of Traumatology and Orthopaedics, University of Tartu, Tartu University Hospital, Tartu 50411, Estonia.
Sulev KõksPerron Institute for Neurological and Translational Science, QEII Medical Centre, Nedlands, WA 6009, Australia.ORCID 0000-0001-6087-6643
The University of Western Australia · AUTartu University Hospital · EEHue University · VNMurdoch University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

impact statementOsteosarcoma (OS, also known as osteogenic sarcoma) is the most common primary malignancy of bone in children and adolescents. The molecular mechanisms of OS are extremely complicated and its molecular mediators remain to be elucidated. We sequenced total RNA from 18 OS bone samples (paired normal-tumor biopsies). We found statistically significant (FDR <0.05) 26 differentially expressed transcript variants of

Indexed as

AdolescentAdultAlternative SplicingChildExonsFemaleGene Expression Regulation, NeoplasticHumansMaleMiddle AgedOsteosarcomaReceptors, LeptinReproducibility of ResultsRNA, MessengerYoung AdultReceptors, LeptinRNA, Messengeralternative splicingLEPROTosteogenic sarcomaOsteosarcomaRNA sequencingtranscriptome

Identifiers

PMID32787464
PMCPMC7553092
OpenAlexW3048914521

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.